Biliary excretion of aluminum in aluminum osteodystrophy with liver disease.
Publication
, Journal Article
Williams, JW; Vera, SR; Peters, TG; Luther, RW; Bhattacharya, S; Spears, H; Graham, A; Pitcock, JA; Crawford, AJ; Palmieri, GM
Published in: Ann Intern Med
June 1986
Two patients with chronic liver disease developed elevated serum aluminum concentrations and biopsy-proven osteodystrophy. Neither patient had chronic renal failure but both had received aluminum-containing antacids for long periods. We measured biliary and urinary aluminum excretion during antacid loading in patients with normal liver function. Our studies show that biliary excretion is an important route of elimination of orally absorbed aluminum, and we suggest that long-term antacid therapy in patients with severe liver disease be monitored with periodic serum and urinary aluminum determinations to avoid aluminum osteodystrophy.
Duke Scholars
Published In
Ann Intern Med
DOI
ISSN
0003-4819
Publication Date
June 1986
Volume
104
Issue
6
Start / End Page
782 / 785
Location
United States
Related Subject Headings
- Liver Diseases
- Humans
- General & Internal Medicine
- Female
- Deferoxamine
- Chronic Disease
- Bone and Bones
- Bone Diseases, Metabolic
- Bile
- Aluminum Hydroxide
Citation
APA
Chicago
ICMJE
MLA
NLM
Williams, J. W., Vera, S. R., Peters, T. G., Luther, R. W., Bhattacharya, S., Spears, H., … Palmieri, G. M. (1986). Biliary excretion of aluminum in aluminum osteodystrophy with liver disease. Ann Intern Med, 104(6), 782–785. https://doi.org/10.7326/0003-4819-104-6-782
Williams, J. W., S. R. Vera, T. G. Peters, R. W. Luther, S. Bhattacharya, H. Spears, A. Graham, J. A. Pitcock, A. J. Crawford, and G. M. Palmieri. “Biliary excretion of aluminum in aluminum osteodystrophy with liver disease.” Ann Intern Med 104, no. 6 (June 1986): 782–85. https://doi.org/10.7326/0003-4819-104-6-782.
Williams JW, Vera SR, Peters TG, Luther RW, Bhattacharya S, Spears H, et al. Biliary excretion of aluminum in aluminum osteodystrophy with liver disease. Ann Intern Med. 1986 Jun;104(6):782–5.
Williams, J. W., et al. “Biliary excretion of aluminum in aluminum osteodystrophy with liver disease.” Ann Intern Med, vol. 104, no. 6, June 1986, pp. 782–85. Pubmed, doi:10.7326/0003-4819-104-6-782.
Williams JW, Vera SR, Peters TG, Luther RW, Bhattacharya S, Spears H, Graham A, Pitcock JA, Crawford AJ, Palmieri GM. Biliary excretion of aluminum in aluminum osteodystrophy with liver disease. Ann Intern Med. 1986 Jun;104(6):782–785.
Published In
Ann Intern Med
DOI
ISSN
0003-4819
Publication Date
June 1986
Volume
104
Issue
6
Start / End Page
782 / 785
Location
United States
Related Subject Headings
- Liver Diseases
- Humans
- General & Internal Medicine
- Female
- Deferoxamine
- Chronic Disease
- Bone and Bones
- Bone Diseases, Metabolic
- Bile
- Aluminum Hydroxide