The therapeutic potential of natural killer cells in neuropathic pain.
Publication
, Journal Article
Kim, HW; Wang, S; Davies, AJ; Oh, SB
Published in: Trends in neurosciences
August 2023
Novel disease-modifying treatments for neuropathic pain are urgently required. The cellular immune response to nerve injury represents a promising target for therapeutic development. Recently, the role of natural killer (NK) cells in both CNS and PNS disease has been the subject of growing interest. In this opinion article, we set out the case for NK cell-based intervention as a promising avenue for development in the management of neuropathic pain. We explore the potential cellular and molecular targets of NK cells in the PNS by contrasting with their reported functional roles in CNS diseases, and we suggest strategies for using the beneficial functions of NK cells and immune-based therapeutics in the context of neuropathic pain.
Duke Scholars
Published In
Trends in neurosciences
DOI
EISSN
1878-108X
ISSN
0166-2236
Publication Date
August 2023
Volume
46
Issue
8
Start / End Page
617 / 627
Related Subject Headings
- Neurology & Neurosurgery
- Neuralgia
- Killer Cells, Natural
- Humans
- 5203 Clinical and health psychology
- 5202 Biological psychology
- 3209 Neurosciences
- 1702 Cognitive Sciences
- 1701 Psychology
- 1109 Neurosciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Kim, H. W., Wang, S., Davies, A. J., & Oh, S. B. (2023). The therapeutic potential of natural killer cells in neuropathic pain. Trends in Neurosciences, 46(8), 617–627. https://doi.org/10.1016/j.tins.2023.05.008
Kim, Hyoung Woo, Shuaiwei Wang, Alexander J. Davies, and Seog Bae Oh. “The therapeutic potential of natural killer cells in neuropathic pain.” Trends in Neurosciences 46, no. 8 (August 2023): 617–27. https://doi.org/10.1016/j.tins.2023.05.008.
Kim HW, Wang S, Davies AJ, Oh SB. The therapeutic potential of natural killer cells in neuropathic pain. Trends in neurosciences. 2023 Aug;46(8):617–27.
Kim, Hyoung Woo, et al. “The therapeutic potential of natural killer cells in neuropathic pain.” Trends in Neurosciences, vol. 46, no. 8, Aug. 2023, pp. 617–27. Epmc, doi:10.1016/j.tins.2023.05.008.
Kim HW, Wang S, Davies AJ, Oh SB. The therapeutic potential of natural killer cells in neuropathic pain. Trends in neurosciences. 2023 Aug;46(8):617–627.
Published In
Trends in neurosciences
DOI
EISSN
1878-108X
ISSN
0166-2236
Publication Date
August 2023
Volume
46
Issue
8
Start / End Page
617 / 627
Related Subject Headings
- Neurology & Neurosurgery
- Neuralgia
- Killer Cells, Natural
- Humans
- 5203 Clinical and health psychology
- 5202 Biological psychology
- 3209 Neurosciences
- 1702 Cognitive Sciences
- 1701 Psychology
- 1109 Neurosciences