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Lymph Node Staging and Treatment in Pediatric Patients With Soft Tissue Sarcomas: A Consensus Opinion From the Children's Oncology Group, European paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.

Publication ,  Journal Article
Terwisscha van Scheltinga, S; Schoot, RA; Routh, JC; Seitz, G; Kao, SC; de Keizer, B; Shulkin, B; Ewijk, RV; McCarville, B; Casey, D; Merks, H ...
Published in: Pediatr Blood Cancer
April 2025

Accurate staging of nodal involvement in pediatric sarcoma patients is important to determine correct systemic and local therapy, with the goal to reduce subsequent recurrences. However, differences in lymph node staging strategies, definitions, and treatment protocols between the Children's Oncology Group (COG), European paediatric Soft tissue sarcoma Study Group (EpSSG), and the Cooperative Weichteilsarkom Studiengruppe (CWS) complicate comparisons. In this article, we aim to establish internationally recognized recommendations for lymph node assessment and treatment of children and adolescents diagnosed with rhabdomyosarcoma (RMS) and non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) according to the Consensus Conference Standard Operating Procedure methodology.

Duke Scholars

Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

April 2025

Volume

72

Issue

4

Start / End Page

e31538

Location

United States

Related Subject Headings

  • Sarcoma
  • Rhabdomyosarcoma
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Lymphatic Metastasis
  • Lymph Nodes
  • Humans
  • Europe
  • Consensus
  • Child, Preschool
 

Citation

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Terwisscha van Scheltinga, S., Schoot, R. A., Routh, J. C., Seitz, G., Kao, S. C., de Keizer, B., … Rodeberg, D. (2025). Lymph Node Staging and Treatment in Pediatric Patients With Soft Tissue Sarcomas: A Consensus Opinion From the Children's Oncology Group, European paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe. Pediatr Blood Cancer, 72(4), e31538. https://doi.org/10.1002/pbc.31538
Terwisscha van Scheltinga, Sheila, Reineke A. Schoot, Jonathan C. Routh, Guido Seitz, Simon C. Kao, Bart de Keizer, Barry Shulkin, et al. “Lymph Node Staging and Treatment in Pediatric Patients With Soft Tissue Sarcomas: A Consensus Opinion From the Children's Oncology Group, European paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.Pediatr Blood Cancer 72, no. 4 (April 2025): e31538. https://doi.org/10.1002/pbc.31538.
Terwisscha van Scheltinga S, Schoot RA, Routh JC, Seitz G, Kao SC, de Keizer B, Shulkin B, Ewijk RV, McCarville B, Casey D, Allen-Rhoades W, Mercolini F, Merks H, Orbach D, Kapadia T, Walterhouse DO, Davila Fajardo R, Hiemcke-Jiwa L, Franzius C, De Corti F, Tang V, Metts J, Oberoi S, Vokuhl C, Dasgupta R, Birz S, Rodeberg D. Lymph Node Staging and Treatment in Pediatric Patients With Soft Tissue Sarcomas: A Consensus Opinion From the Children's Oncology Group, European paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe. Pediatr Blood Cancer. 2025 Apr;72(4):e31538.
Journal cover image

Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

April 2025

Volume

72

Issue

4

Start / End Page

e31538

Location

United States

Related Subject Headings

  • Sarcoma
  • Rhabdomyosarcoma
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Lymphatic Metastasis
  • Lymph Nodes
  • Humans
  • Europe
  • Consensus
  • Child, Preschool