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How epigenetic inheritance fails to explain the Black-White health gap.

Publication ,  Journal Article
Charney, E; Darity, W; Hubbard, L
Published in: Social science & medicine (1982)
February 2025

Slavery, legal segregation, and ongoing discrimination have exacted an unfathomable toll on the black population in the United States, particularly with respect to the impact on health outcomes. In recent years, various researchers and activists have suggested that racial disparities in the modern era can be attributed directly to the trauma of slavery, postulating that these unspeakable traumas led to epigenetic changes in slaves-changes that have since been passed down to subsequent generations. Investigating those claims in this paper, we comprise a review of previous literature that considers the potential for transgenerational epigenetic transmission of trauma in humans. However, we find that there is little evidence to indicate the presence of transgenerational epigenetic transmission of trauma in humans. We find no prior evidence that supports (or is relevant to) the notion that the black-white health gap stems from the inherited trauma of slavery. We conclude that, given the ongoing traumas black Americans are exposed to in modern America, it is much more likely that present-day racial health disparities are due to more direct and current mechanisms than transgenerational transmission of slavery-era trauma.

Duke Scholars

Published In

Social science & medicine (1982)

DOI

EISSN

1873-5347

ISSN

0277-9536

Publication Date

February 2025

Volume

366

Start / End Page

117697

Related Subject Headings

  • White
  • United States
  • Racism
  • Public Health
  • Humans
  • Health Status Disparities
  • Epigenesis, Genetic
  • Enslavement
  • Black or African American
  • 44 Human society
 

Citation

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Charney, E., Darity, W., & Hubbard, L. (2025). How epigenetic inheritance fails to explain the Black-White health gap. Social Science & Medicine (1982), 366, 117697. https://doi.org/10.1016/j.socscimed.2025.117697
Charney, Evan, William Darity, and Lucas Hubbard. “How epigenetic inheritance fails to explain the Black-White health gap.Social Science & Medicine (1982) 366 (February 2025): 117697. https://doi.org/10.1016/j.socscimed.2025.117697.
Charney E, Darity W, Hubbard L. How epigenetic inheritance fails to explain the Black-White health gap. Social science & medicine (1982). 2025 Feb;366:117697.
Charney, Evan, et al. “How epigenetic inheritance fails to explain the Black-White health gap.Social Science & Medicine (1982), vol. 366, Feb. 2025, p. 117697. Epmc, doi:10.1016/j.socscimed.2025.117697.
Charney E, Darity W, Hubbard L. How epigenetic inheritance fails to explain the Black-White health gap. Social science & medicine (1982). 2025 Feb;366:117697.
Journal cover image

Published In

Social science & medicine (1982)

DOI

EISSN

1873-5347

ISSN

0277-9536

Publication Date

February 2025

Volume

366

Start / End Page

117697

Related Subject Headings

  • White
  • United States
  • Racism
  • Public Health
  • Humans
  • Health Status Disparities
  • Epigenesis, Genetic
  • Enslavement
  • Black or African American
  • 44 Human society