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Minimum Requirements to Safely Establish and Sustain New Hepatic Arterial Infusion Pump Programs: An International Expert Perspective.

Publication ,  Journal Article
Merkow, RP; Cavnar, MJ; Gleisner, AL; Mayo, SC; Gholami, S; Karanicolas, PJ; Koerkamp, BG; Homs, MYV; Connell, LC; Cercek, A; Helft, PR ...
Published in: Ann Surg Oncol
June 2025

Hepatic arterial infusion (HAI) pump chemotherapy is an effective therapy for colorectal liver metastases and intrahepatic cholangiocarcinoma. In the setting of recent reports suggesting favorable outcomes in these diseases with HAI, there has been a surge in interest in this treatment worldwide, prompting the opening of many new HAI programs. While significant technical expertise is required for pump implantation, this alone is insufficient to open a safe and sustainable HAI program, and numerous other factors must be considered prior to the first pump implantation. This expert perspective, established using an anonymous web-based survey of experienced multidisciplinary international HAI providers, details the minimum required personnel, expertise, training, and infrastructure to optimize success and sustainability of a safe and effective new HAI program.

Duke Scholars

Published In

Ann Surg Oncol

DOI

EISSN

1534-4681

Publication Date

June 2025

Volume

32

Issue

6

Start / End Page

4408 / 4416

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Liver Neoplasms
  • Infusions, Intra-Arterial
  • Humans
  • Hepatic Artery
  • Colorectal Neoplasms
  • Cholangiocarcinoma
  • Bile Duct Neoplasms
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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MLA
NLM
Merkow, R. P., Cavnar, M. J., Gleisner, A. L., Mayo, S. C., Gholami, S., Karanicolas, P. J., … Lidsky, M. E. (2025). Minimum Requirements to Safely Establish and Sustain New Hepatic Arterial Infusion Pump Programs: An International Expert Perspective. Ann Surg Oncol, 32(6), 4408–4416. https://doi.org/10.1245/s10434-025-17009-1
Merkow, Ryan P., Michael J. Cavnar, Ana L. Gleisner, Skye C. Mayo, Sepideh Gholami, Paul J. Karanicolas, Bas Groot Koerkamp, et al. “Minimum Requirements to Safely Establish and Sustain New Hepatic Arterial Infusion Pump Programs: An International Expert Perspective.Ann Surg Oncol 32, no. 6 (June 2025): 4408–16. https://doi.org/10.1245/s10434-025-17009-1.
Merkow RP, Cavnar MJ, Gleisner AL, Mayo SC, Gholami S, Karanicolas PJ, et al. Minimum Requirements to Safely Establish and Sustain New Hepatic Arterial Infusion Pump Programs: An International Expert Perspective. Ann Surg Oncol. 2025 Jun;32(6):4408–16.
Merkow, Ryan P., et al. “Minimum Requirements to Safely Establish and Sustain New Hepatic Arterial Infusion Pump Programs: An International Expert Perspective.Ann Surg Oncol, vol. 32, no. 6, June 2025, pp. 4408–16. Pubmed, doi:10.1245/s10434-025-17009-1.
Merkow RP, Cavnar MJ, Gleisner AL, Mayo SC, Gholami S, Karanicolas PJ, Koerkamp BG, Homs MYV, Connell LC, Cercek A, Helft PR, Polite BN, Patel RA, Uronis HE, D’Angelica M, Lidsky ME. Minimum Requirements to Safely Establish and Sustain New Hepatic Arterial Infusion Pump Programs: An International Expert Perspective. Ann Surg Oncol. 2025 Jun;32(6):4408–4416.
Journal cover image

Published In

Ann Surg Oncol

DOI

EISSN

1534-4681

Publication Date

June 2025

Volume

32

Issue

6

Start / End Page

4408 / 4416

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Liver Neoplasms
  • Infusions, Intra-Arterial
  • Humans
  • Hepatic Artery
  • Colorectal Neoplasms
  • Cholangiocarcinoma
  • Bile Duct Neoplasms
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis