Clinical neurocardiology: defining the value of neuroscience-based cardiovascular therapeutics - 2024 update.
Publication
, Journal Article
Ajijola, OA; Aksu, T; Arora, R; Biaggioni, I; Chen, P-S; De Ferrari, G; Dusi, V; Fudim, M; Goldberger, JJ; Green, AL; Herring, N; Khalsa, SS ...
Published in: J Physiol
March 2025
The intricate role of the autonomic nervous system (ANS) in regulating cardiac physiology has long been recognized. Aberrant function of the ANS is central to the pathophysiology of cardiovascular diseases. It stands to reason, therefore, that neuroscience-based cardiovascular therapeutics hold great promise in the treatment of cardiovascular diseases in humans. A decade after the inaugural edition, this White Paper reviews the current state of understanding of human cardiac neuroanatomy, neurophysiology and pathophysiology in specific disease conditions, autonomic testing, risk stratification, and neuromodulatory strategies to mitigate the progression of cardiovascular diseases.
Duke Scholars
Published In
J Physiol
DOI
EISSN
1469-7793
Publication Date
March 2025
Volume
603
Issue
7
Start / End Page
1781 / 1839
Location
England
Related Subject Headings
- Physiology
- Neurosciences
- Humans
- Heart
- Cardiovascular Diseases
- Autonomic Nervous System
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Ajijola, O. A., Aksu, T., Arora, R., Biaggioni, I., Chen, P.-S., De Ferrari, G., … Shivkumar, K. (2025). Clinical neurocardiology: defining the value of neuroscience-based cardiovascular therapeutics - 2024 update. J Physiol, 603(7), 1781–1839. https://doi.org/10.1113/JP284741
Ajijola, Olujimi A., Tolga Aksu, Rishi Arora, Italo Biaggioni, Peng-Sheng Chen, Gaetano De Ferrari, Veronica Dusi, et al. “Clinical neurocardiology: defining the value of neuroscience-based cardiovascular therapeutics - 2024 update.” J Physiol 603, no. 7 (March 2025): 1781–1839. https://doi.org/10.1113/JP284741.
Ajijola OA, Aksu T, Arora R, Biaggioni I, Chen P-S, De Ferrari G, et al. Clinical neurocardiology: defining the value of neuroscience-based cardiovascular therapeutics - 2024 update. J Physiol. 2025 Mar;603(7):1781–839.
Ajijola, Olujimi A., et al. “Clinical neurocardiology: defining the value of neuroscience-based cardiovascular therapeutics - 2024 update.” J Physiol, vol. 603, no. 7, Mar. 2025, pp. 1781–839. Pubmed, doi:10.1113/JP284741.
Ajijola OA, Aksu T, Arora R, Biaggioni I, Chen P-S, De Ferrari G, Dusi V, Fudim M, Goldberger JJ, Green AL, Herring N, Khalsa SS, Kumar R, Lakatta E, Mehra R, Meyer C, Po S, Stavrakis S, Somers VK, Tan AY, Valderrabano M, Shivkumar K. Clinical neurocardiology: defining the value of neuroscience-based cardiovascular therapeutics - 2024 update. J Physiol. 2025 Mar;603(7):1781–1839.
Published In
J Physiol
DOI
EISSN
1469-7793
Publication Date
March 2025
Volume
603
Issue
7
Start / End Page
1781 / 1839
Location
England
Related Subject Headings
- Physiology
- Neurosciences
- Humans
- Heart
- Cardiovascular Diseases
- Autonomic Nervous System
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences