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Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.

Publication ,  Journal Article
Aykut, B; Overbey, DM; Medina, CK; Omer, TM; Rajab, TK; Ngeve, SM; Beckerman, Z; Turek, JW
Published in: Ann Thorac Surg Short Rep
March 2025

BACKGROUND: Partial heart transplantation (PHT) has emerged as a pioneering approach for treating infants with irreparable heart valve dysfunction. However, the scarcity of suitable donors presents a significant bottleneck to its widespread application. This study introduces and evaluates the novel use of domino and split-root procedures within PHT. METHODS: We describe 6 pediatric cardiac patients who underwent either domino or split-root PHT at our institution. RESULTS: From May to August 2023, our team successfully executed 3 domino and 3 split-root PHTs, including 1 procedure that involved interinstitutional collaboration. These cases highlight the procedural feasibility and the potential for broader application. CONCLUSIONS: The implementation of PHT represents a significant advance in pediatric heart care. Domino and split-root techniques within the PHT framework have the potential to substantially increase both donor availability and recipient capacity. These strategies usher in a new era of organ stewardship through addressing the challenge of donor organ shortage.

Duke Scholars

Published In

Ann Thorac Surg Short Rep

DOI

EISSN

2772-9931

Publication Date

March 2025

Volume

3

Issue

1

Start / End Page

86 / 91

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Aykut, B., Overbey, D. M., Medina, C. K., Omer, T. M., Rajab, T. K., Ngeve, S. M., … Turek, J. W. (2025). Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots. Ann Thorac Surg Short Rep, 3(1), 86–91. https://doi.org/10.1016/j.atssr.2024.07.033
Aykut, Berk, Douglas M. Overbey, Cathlyn K. Medina, Tariq M. Omer, T Konrad Rajab, Smith M. Ngeve, Ziv Beckerman, and Joseph W. Turek. “Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.Ann Thorac Surg Short Rep 3, no. 1 (March 2025): 86–91. https://doi.org/10.1016/j.atssr.2024.07.033.
Aykut B, Overbey DM, Medina CK, Omer TM, Rajab TK, Ngeve SM, et al. Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots. Ann Thorac Surg Short Rep. 2025 Mar;3(1):86–91.
Aykut, Berk, et al. “Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.Ann Thorac Surg Short Rep, vol. 3, no. 1, Mar. 2025, pp. 86–91. Pubmed, doi:10.1016/j.atssr.2024.07.033.
Aykut B, Overbey DM, Medina CK, Omer TM, Rajab TK, Ngeve SM, Beckerman Z, Turek JW. Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots. Ann Thorac Surg Short Rep. 2025 Mar;3(1):86–91.

Published In

Ann Thorac Surg Short Rep

DOI

EISSN

2772-9931

Publication Date

March 2025

Volume

3

Issue

1

Start / End Page

86 / 91

Location

United States