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Latarjet procedure for patients with pre-existing seizure disorders vs. controls: a systematic review and meta-analysis.

Publication ,  Journal Article
O'Sullivan, D; Davey, MS; Hurley, ET; Dickens, JF; Mullett, H
Published in: J Shoulder Elbow Surg
July 2025

BACKGROUND: The purpose of this study was to systematically review the literature to ascertain the clinical outcomes of the Latarjet procedure in patients with seizure disorders (SDs) vs. controls. METHODS: Two independent reviewers performed a literature search using the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines using PubMed, Embase, and Scopus databases. Only studies reporting on outcomes of the Latarjet procedure comparing patients with pre-existing SDs or those comparing such patients vs. controls were considered for inclusion. A meta-analysis was performed on clinical outcomes compared using RevMan. RESULTS: The search found 5 studies including 237 shoulders (78% males), with an average age of 28.9 ± 2.5 years (19-55) and mean follow-up of 55 ± 31.7 months (12-240). Both the control and SD groups reported significant increases in the Rowe and American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form scores postoperatively (both P < .001). Additionally, there were significantly higher Rowe scores reported in the control group post-Latarjet procedures when compared to the SD group (94.4 ± 0.1 vs. 85.2 ± 7.9, P < .001). The meta-analysis demonstrated that there were significantly higher recurrence rates and revision rates in those who underwent a Latarjet procedure with pre-existing SD, vs. those in the control group (11.2% vs. 2.5%, P = .01) and 14.3% vs. control 0.01% (P < .01). CONCLUSION: Our review found that patients with pre-existing SD were significantly more likely to report higher rates of postoperative recurrence and poorer functional outcomes following a Latarjet procedure, when compared to controls. Therefore, the presence of pre-existing SD warrants consideration in the management algorithm for patients with anterior shoulder instability.

Duke Scholars

Published In

J Shoulder Elbow Surg

DOI

EISSN

1532-6500

Publication Date

July 2025

Volume

34

Issue

7

Start / End Page

1841 / 1846

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Shoulder Joint
  • Orthopedics
  • Male
  • Joint Instability
  • Humans
  • Epilepsy
  • Adult
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
O’Sullivan, D., Davey, M. S., Hurley, E. T., Dickens, J. F., & Mullett, H. (2025). Latarjet procedure for patients with pre-existing seizure disorders vs. controls: a systematic review and meta-analysis. J Shoulder Elbow Surg, 34(7), 1841–1846. https://doi.org/10.1016/j.jse.2024.10.002
O’Sullivan, David, Martin S. Davey, Eoghan T. Hurley, Jonathan F. Dickens, and Hannan Mullett. “Latarjet procedure for patients with pre-existing seizure disorders vs. controls: a systematic review and meta-analysis.J Shoulder Elbow Surg 34, no. 7 (July 2025): 1841–46. https://doi.org/10.1016/j.jse.2024.10.002.
O’Sullivan D, Davey MS, Hurley ET, Dickens JF, Mullett H. Latarjet procedure for patients with pre-existing seizure disorders vs. controls: a systematic review and meta-analysis. J Shoulder Elbow Surg. 2025 Jul;34(7):1841–6.
O’Sullivan, David, et al. “Latarjet procedure for patients with pre-existing seizure disorders vs. controls: a systematic review and meta-analysis.J Shoulder Elbow Surg, vol. 34, no. 7, July 2025, pp. 1841–46. Pubmed, doi:10.1016/j.jse.2024.10.002.
O’Sullivan D, Davey MS, Hurley ET, Dickens JF, Mullett H. Latarjet procedure for patients with pre-existing seizure disorders vs. controls: a systematic review and meta-analysis. J Shoulder Elbow Surg. 2025 Jul;34(7):1841–1846.
Journal cover image

Published In

J Shoulder Elbow Surg

DOI

EISSN

1532-6500

Publication Date

July 2025

Volume

34

Issue

7

Start / End Page

1841 / 1846

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Shoulder Joint
  • Orthopedics
  • Male
  • Joint Instability
  • Humans
  • Epilepsy
  • Adult
  • 3202 Clinical sciences
  • 1103 Clinical Sciences