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Summation and recommendations for the safe and effective use of topical and oral minoxidil.

Publication ,  Journal Article
Olsen, EA; Sinclair, R; Hordinsky, M; Mesinkovska, NA; Sadick, N; Shapiro, J; Bergfeld, W
Published in: J Am Acad Dermatol
August 2025

BACKGROUND: Topical minoxidil, approved for the treatment of androgenetic alopecia, also has efficacy in many other hair loss disorders, its use is limited due to the need for at least daily application. Oral minoxidil, in doses below those likely to lower blood pressure (so called "low dose oral minoxidil") has increasingly been used off label to treat a variety of hair loss conditions but without any standard recommended best practices. OBJECTIVES: To provide a review of how experts in hair loss use the available literature on topical and low dose oral minoxidil to educate and treat safely and effectively patients with hair loss. METHODS: Dermatologists with expertise in hair disorders met by teleconference and email to review the literature and share their direct experience with topical and oral minoxidil. RESULTS: Provision of basic knowledge of the key aspects of the use of topical or oral minoxidil to insure safe and effective use of either in treating hair loss.

Duke Scholars

Published In

J Am Acad Dermatol

DOI

EISSN

1097-6787

Publication Date

August 2025

Volume

93

Issue

2

Start / End Page

457 / 465

Location

United States

Related Subject Headings

  • Vasodilator Agents
  • Practice Guidelines as Topic
  • Minoxidil
  • Humans
  • Dermatology & Venereal Diseases
  • Alopecia
  • Administration, Topical
  • Administration, Oral
  • Administration, Cutaneous
  • 3202 Clinical sciences
 

Citation

APA
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ICMJE
MLA
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Olsen, E. A., Sinclair, R., Hordinsky, M., Mesinkovska, N. A., Sadick, N., Shapiro, J., & Bergfeld, W. (2025). Summation and recommendations for the safe and effective use of topical and oral minoxidil. J Am Acad Dermatol, 93(2), 457–465. https://doi.org/10.1016/j.jaad.2025.04.016
Olsen, Elise A., Rodney Sinclair, Maria Hordinsky, Natasha A. Mesinkovska, Neil Sadick, Jerry Shapiro, and Wilma Bergfeld. “Summation and recommendations for the safe and effective use of topical and oral minoxidil.J Am Acad Dermatol 93, no. 2 (August 2025): 457–65. https://doi.org/10.1016/j.jaad.2025.04.016.
Olsen EA, Sinclair R, Hordinsky M, Mesinkovska NA, Sadick N, Shapiro J, et al. Summation and recommendations for the safe and effective use of topical and oral minoxidil. J Am Acad Dermatol. 2025 Aug;93(2):457–65.
Olsen, Elise A., et al. “Summation and recommendations for the safe and effective use of topical and oral minoxidil.J Am Acad Dermatol, vol. 93, no. 2, Aug. 2025, pp. 457–65. Pubmed, doi:10.1016/j.jaad.2025.04.016.
Olsen EA, Sinclair R, Hordinsky M, Mesinkovska NA, Sadick N, Shapiro J, Bergfeld W. Summation and recommendations for the safe and effective use of topical and oral minoxidil. J Am Acad Dermatol. 2025 Aug;93(2):457–465.
Journal cover image

Published In

J Am Acad Dermatol

DOI

EISSN

1097-6787

Publication Date

August 2025

Volume

93

Issue

2

Start / End Page

457 / 465

Location

United States

Related Subject Headings

  • Vasodilator Agents
  • Practice Guidelines as Topic
  • Minoxidil
  • Humans
  • Dermatology & Venereal Diseases
  • Alopecia
  • Administration, Topical
  • Administration, Oral
  • Administration, Cutaneous
  • 3202 Clinical sciences