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Postoperative Lung Transplant Considerations in the Older Recipient.

Publication ,  Journal Article
Hanna, S; Beermann, K; Levine, DJ; Loor, G; Singer, JP; Smith, PJ; Ali, HA
Published in: Chest
August 2025

TOPIC IMPORTANCE: Lung transplantation (LTx) remains the ultimate treatment for many patients with advanced lung disease. Although the age cutoffs for LTx have been debated due to variable outcomes, the number of LTx procedures performed on patients aged ≥ 65 years has significantly increased in recent decades, reflecting the realities of an aging demographic. This trend underscores the unique management challenges faced by this cohort and highlights the importance of addressing evidence gaps in their perioperative and postoperative care. REVIEW FINDINGS: This literature review highlights that, despite the challenges, recent data indicate favorable outcomes for patients aged ≥ 65 years undergoing LTx. Although this article primarily focuses on postoperative care, it also addresses some perioperative considerations, including the use of extracorporeal life support as well as the choice of the procedure type and donor considerations. It additionally incorporates current knowledge about early and late postoperative complications, including neurologic, cardiovascular, and renal, among others, along with their management strategies and current practice patterns. SUMMARY: In conclusion, this review emphasizes the need to optimize care for older LTx recipients. The evidence regarding ideal management practices for this population is limited. We highlight the necessity for comprehensive postoperative management guidelines and identify key areas for further research to establish evidence-based protocols for this growing demographic.

Duke Scholars

Published In

Chest

DOI

EISSN

1931-3543

Publication Date

August 2025

Volume

168

Issue

2

Start / End Page

435 / 448

Location

United States

Related Subject Headings

  • Respiratory System
  • Postoperative Complications
  • Postoperative Care
  • Lung Transplantation
  • Lung Diseases
  • Humans
  • Aged
  • Age Factors
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hanna, S., Beermann, K., Levine, D. J., Loor, G., Singer, J. P., Smith, P. J., & Ali, H. A. (2025). Postoperative Lung Transplant Considerations in the Older Recipient. Chest, 168(2), 435–448. https://doi.org/10.1016/j.chest.2024.10.060
Hanna, Sandrine, Kristi Beermann, Deborah J. Levine, Gabriel Loor, Jonathan P. Singer, Patrick J. Smith, and Hakim Azfar Ali. “Postoperative Lung Transplant Considerations in the Older Recipient.Chest 168, no. 2 (August 2025): 435–48. https://doi.org/10.1016/j.chest.2024.10.060.
Hanna S, Beermann K, Levine DJ, Loor G, Singer JP, Smith PJ, et al. Postoperative Lung Transplant Considerations in the Older Recipient. Chest. 2025 Aug;168(2):435–48.
Hanna, Sandrine, et al. “Postoperative Lung Transplant Considerations in the Older Recipient.Chest, vol. 168, no. 2, Aug. 2025, pp. 435–48. Pubmed, doi:10.1016/j.chest.2024.10.060.
Hanna S, Beermann K, Levine DJ, Loor G, Singer JP, Smith PJ, Ali HA. Postoperative Lung Transplant Considerations in the Older Recipient. Chest. 2025 Aug;168(2):435–448.

Published In

Chest

DOI

EISSN

1931-3543

Publication Date

August 2025

Volume

168

Issue

2

Start / End Page

435 / 448

Location

United States

Related Subject Headings

  • Respiratory System
  • Postoperative Complications
  • Postoperative Care
  • Lung Transplantation
  • Lung Diseases
  • Humans
  • Aged
  • Age Factors
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology