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Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma.

Publication ,  Journal Article
Musmar, B; Roy, JM; Spellicy, S; Tjoumakaris, SI; Gooch, MR; Rosenwasser, RH; Hasan, D; Jabbour, P
Published in: J Neurosurg Sci
April 2025

Chronic subdural hematoma (cSDH) presents a multifaceted challenge in contemporary neurological practice, necessitating innovative therapeutic strategies. This comprehensive review explores the convergence of two promising interventions: statins and middle meningeal artery (MMA) Embolization. With cSDH incidence on the rise, particularly among the aging population and those with long-term anticoagulant usage, the traditional surgical avenues face limitations in recurrence rates and associated risk factors. Statins, heralded for their anti-inflammatory, vasculogenic, and angiogenic properties, are emerging as potential allies in cSDH management. Concurrently, MMA embolization offers a nuanced approach to target the neomembrane's blood supply, with evidence supporting its efficacy and safety. However, the synthesis of MMA embolization with statins remains relatively unexplored, presenting a complex interplay between inflammation modulation and blood supply interruption.

Duke Scholars

Published In

J Neurosurg Sci

DOI

EISSN

1827-1855

Publication Date

April 2025

Volume

69

Issue

2

Start / End Page

218 / 224

Location

Italy

Related Subject Headings

  • Neurology & Neurosurgery
  • Meningeal Arteries
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Humans
  • Hematoma, Subdural, Chronic
  • Embolization, Therapeutic
 

Citation

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Musmar, B., Roy, J. M., Spellicy, S., Tjoumakaris, S. I., Gooch, M. R., Rosenwasser, R. H., … Jabbour, P. (2025). Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma. J Neurosurg Sci, 69(2), 218–224. https://doi.org/10.23736/S0390-5616.25.06426-4
Musmar, Basel, Joanna M. Roy, Samantha Spellicy, Stavropoula I. Tjoumakaris, Michael R. Gooch, Robert H. Rosenwasser, David Hasan, and Pascal Jabbour. “Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma.J Neurosurg Sci 69, no. 2 (April 2025): 218–24. https://doi.org/10.23736/S0390-5616.25.06426-4.
Musmar B, Roy JM, Spellicy S, Tjoumakaris SI, Gooch MR, Rosenwasser RH, et al. Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma. J Neurosurg Sci. 2025 Apr;69(2):218–24.
Musmar, Basel, et al. “Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma.J Neurosurg Sci, vol. 69, no. 2, Apr. 2025, pp. 218–24. Pubmed, doi:10.23736/S0390-5616.25.06426-4.
Musmar B, Roy JM, Spellicy S, Tjoumakaris SI, Gooch MR, Rosenwasser RH, Hasan D, Jabbour P. Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma. J Neurosurg Sci. 2025 Apr;69(2):218–224.

Published In

J Neurosurg Sci

DOI

EISSN

1827-1855

Publication Date

April 2025

Volume

69

Issue

2

Start / End Page

218 / 224

Location

Italy

Related Subject Headings

  • Neurology & Neurosurgery
  • Meningeal Arteries
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Humans
  • Hematoma, Subdural, Chronic
  • Embolization, Therapeutic