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Side Effect Profiles of Nonhormonal, Nonsurgical Gender-Affirming Body Modifications.

Publication ,  Journal Article
Schwartz, BL; Tran, NK; Mayo, JA; Peitzmeier, SM; Poteat, TC; Lubensky, ME; Flentje, A; Obedin-Maliver, J; Lunn, MR
Published in: LGBT health
October 2025

Purpose: Binding, packing, using stand-to-pee (STP) devices, and tucking are nonhormonal, nonsurgical gender-affirming body modifications (GABMs) that are used to affirm gender expression. This study sought to describe the sociodemographic characteristics of and side effects experienced by those using GABMs. Methods: We conducted a cross-sectional study of The Population Research in Identity and Disparities for Equality Study participants who completed the 2023 Annual Questionnaire. Data on sociodemographics and self-reported side effects were collected and analyzed using descriptive statistics. Results: Of 6296 participants, 1694 reported GABMs including binding (n = 995), packing (n = 590), using an STP device (n = 351), and tucking (n = 265). Each GABM had a distinct side effect profile. Pain (2.0%-48.2% past-year prevalence) and dermatologic concerns (0.5%-23.2% past-year prevalence) were reported across GABMs. Conclusion: While GABMs promote mental health and patient safety, they carry a risk of adverse physical health effects. Providers play a vital role in managing GABM-associated side effects to ensure patients can continue to affirm their gender identities.

Duke Scholars

Published In

LGBT health

DOI

EISSN

2325-8306

ISSN

2325-8292

Publication Date

October 2025

Volume

12

Issue

7

Start / End Page

551 / 558

Related Subject Headings

  • Young Adult
  • Transgender Persons
  • Surveys and Questionnaires
  • Middle Aged
  • Male
  • Humans
  • Gender-Affirming Procedures
  • Female
  • Cross-Sectional Studies
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Schwartz, B. L., Tran, N. K., Mayo, J. A., Peitzmeier, S. M., Poteat, T. C., Lubensky, M. E., … Lunn, M. R. (2025). Side Effect Profiles of Nonhormonal, Nonsurgical Gender-Affirming Body Modifications. LGBT Health, 12(7), 551–558. https://doi.org/10.1089/lgbt.2024.0319
Schwartz, Ben L., Nguyen K. Tran, Jonathan A. Mayo, Sarah M. Peitzmeier, Tonia C. Poteat, Micah E. Lubensky, Annesa Flentje, Juno Obedin-Maliver, and Mitchell R. Lunn. “Side Effect Profiles of Nonhormonal, Nonsurgical Gender-Affirming Body Modifications.LGBT Health 12, no. 7 (October 2025): 551–58. https://doi.org/10.1089/lgbt.2024.0319.
Schwartz BL, Tran NK, Mayo JA, Peitzmeier SM, Poteat TC, Lubensky ME, et al. Side Effect Profiles of Nonhormonal, Nonsurgical Gender-Affirming Body Modifications. LGBT health. 2025 Oct;12(7):551–8.
Schwartz, Ben L., et al. “Side Effect Profiles of Nonhormonal, Nonsurgical Gender-Affirming Body Modifications.LGBT Health, vol. 12, no. 7, Oct. 2025, pp. 551–58. Epmc, doi:10.1089/lgbt.2024.0319.
Schwartz BL, Tran NK, Mayo JA, Peitzmeier SM, Poteat TC, Lubensky ME, Flentje A, Obedin-Maliver J, Lunn MR. Side Effect Profiles of Nonhormonal, Nonsurgical Gender-Affirming Body Modifications. LGBT health. 2025 Oct;12(7):551–558.
Journal cover image

Published In

LGBT health

DOI

EISSN

2325-8306

ISSN

2325-8292

Publication Date

October 2025

Volume

12

Issue

7

Start / End Page

551 / 558

Related Subject Headings

  • Young Adult
  • Transgender Persons
  • Surveys and Questionnaires
  • Middle Aged
  • Male
  • Humans
  • Gender-Affirming Procedures
  • Female
  • Cross-Sectional Studies
  • Adult