Cholecystokinin from Gallbladder to Cognition and Beyond
Intestinal cholecystokinin secretion
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, Chapter
Chandra, R; Liddle, RA
January 1, 2025
Cholecystokinin (CCK) is produced in the gastrointestinal tract and brain. In the intestine, the hormone is produced by specialized mucosal enteroendocrine cells, which have their apical end exposed to the intestinal lumen. Ingested food molecules, such as proteins, fats, and carbohydrates, stimulate the cells, which then release CCK into the blood. In addition, enteroendocrine cells interact directly with enteric nerves. By both these mechanisms, CCK stimulates target organs, such as the gall bladder, pancreas (both exocrine and endocrine), stomach, liver, and brain. This chapter describes gastrointestinal enteroendocrine cells, the mechanism of CCK secretion, and the effects of secreted CCK on target tissues.
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Chandra, R., & Liddle, R. A. (2025). Intestinal cholecystokinin secretion. In Cholecystokinin from Gallbladder to Cognition and Beyond (pp. 195–217). https://doi.org/10.1016/B978-0-443-23720-1.00015-0
Chandra, R., and R. A. Liddle. “Intestinal cholecystokinin secretion.” In Cholecystokinin from Gallbladder to Cognition and Beyond, 195–217, 2025. https://doi.org/10.1016/B978-0-443-23720-1.00015-0.
Chandra R, Liddle RA. Intestinal cholecystokinin secretion. In: Cholecystokinin from Gallbladder to Cognition and Beyond. 2025. p. 195–217.
Chandra, R., and R. A. Liddle. “Intestinal cholecystokinin secretion.” Cholecystokinin from Gallbladder to Cognition and Beyond, 2025, pp. 195–217. Scopus, doi:10.1016/B978-0-443-23720-1.00015-0.
Chandra R, Liddle RA. Intestinal cholecystokinin secretion. Cholecystokinin from Gallbladder to Cognition and Beyond. 2025. p. 195–217.