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The Application of Deep Learning for Lymph Node Segmentation: A Systematic Review

Publication ,  Journal Article
Qu, J; Han, X; Chui, ML; Pu, Y; Gunda, ST; Chen, Z; Qin, J; King, AD; Chu, WCW; Cai, J; Ying, MTC
Published in: IEEE Access
January 1, 2025

Automatic lymph node segmentation is the cornerstone for advances in computer vision tasks for early detection and staging of cancer. Traditional segmentation methods are constrained by manual delineation and variability in operator proficiency, limiting their ability to achieve high accuracy. The introduction of deep learning technologies offers new possibilities for improving the accuracy of lymph node image analysis. This study evaluates the application of deep learning in lymph node segmentation and discusses the methodologies of various deep learning architectures such as convolutional neural networks, encoder-decoder networks, and transformers in analyzing medical imaging data across different modalities. Despite the advancements, it still confronts challenges like the shape diversity of lymph nodes, the scarcity of accurately labeled datasets, and the inadequate development of methods that are robust and generalizable across different imaging modalities. To the best of our knowledge, this is the first study that provides a comprehensive overview of the application of deep learning techniques in lymph node segmentation task. Furthermore, this study also explores potential future research directions, including multimodal fusion techniques, transfer learning, and the use of large-scale pre-trained models to overcome current limitations while enhancing cancer diagnosis and treatment planning strategies.

Duke Scholars

Published In

IEEE Access

DOI

EISSN

2169-3536

Publication Date

January 1, 2025

Volume

13

Start / End Page

97208 / 97227

Related Subject Headings

  • 46 Information and computing sciences
  • 40 Engineering
  • 10 Technology
  • 09 Engineering
  • 08 Information and Computing Sciences
 

Citation

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Qu, J., Han, X., Chui, M. L., Pu, Y., Gunda, S. T., Chen, Z., … Ying, M. T. C. (2025). The Application of Deep Learning for Lymph Node Segmentation: A Systematic Review. IEEE Access, 13, 97208–97227. https://doi.org/10.1109/ACCESS.2025.3575454
Qu, J., X. Han, M. L. Chui, Y. Pu, S. T. Gunda, Z. Chen, J. Qin, et al. “The Application of Deep Learning for Lymph Node Segmentation: A Systematic Review.” IEEE Access 13 (January 1, 2025): 97208–27. https://doi.org/10.1109/ACCESS.2025.3575454.
Qu J, Han X, Chui ML, Pu Y, Gunda ST, Chen Z, et al. The Application of Deep Learning for Lymph Node Segmentation: A Systematic Review. IEEE Access. 2025 Jan 1;13:97208–27.
Qu, J., et al. “The Application of Deep Learning for Lymph Node Segmentation: A Systematic Review.” IEEE Access, vol. 13, Jan. 2025, pp. 97208–27. Scopus, doi:10.1109/ACCESS.2025.3575454.
Qu J, Han X, Chui ML, Pu Y, Gunda ST, Chen Z, Qin J, King AD, Chu WCW, Cai J, Ying MTC. The Application of Deep Learning for Lymph Node Segmentation: A Systematic Review. IEEE Access. 2025 Jan 1;13:97208–97227.

Published In

IEEE Access

DOI

EISSN

2169-3536

Publication Date

January 1, 2025

Volume

13

Start / End Page

97208 / 97227

Related Subject Headings

  • 46 Information and computing sciences
  • 40 Engineering
  • 10 Technology
  • 09 Engineering
  • 08 Information and Computing Sciences