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Kidney transplantation using a pediatric en bloc graft after normothermic regional perfusion and donation after circulatory death procurement.

Publication ,  Journal Article
Howard, B; Jundi, MS; Overbey, DM; Turek, JW; Perez, RV; Goussous, N
Published in: Am J Transplant
December 2025

Kidney transplantation is the ultimate treatment for patients with end stage renal disease. However, with the expanding gap between organ supply and demand, utilization of organs from extended-criteria donors is an important strategy to address this problem. The adoption of normothermic regional perfusion (NRP) after donation after circulatory death has been shown to increase organ utilization and posttransplant outcomes. In this case report, we present the first reported case of a successful kidney transplantation and 1-year follow-up using an en bloc graft from a 2-month-old infant who underwent NRP-donation after circulatory death procurement. This case demonstrates that utilization of NRP in pediatric donors can help expand organ utilization.

Duke Scholars

Published In

Am J Transplant

DOI

EISSN

1600-6143

Publication Date

December 2025

Volume

25

Issue

12

Start / End Page

2646 / 2650

Location

United States

Related Subject Headings

  • Tissue and Organ Procurement
  • Tissue Donors
  • Surgery
  • Prognosis
  • Perfusion
  • Organ Preservation
  • Male
  • Kidney Transplantation
  • Kidney Failure, Chronic
  • Infant
 

Citation

APA
Chicago
ICMJE
MLA
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Howard, B., Jundi, M. S., Overbey, D. M., Turek, J. W., Perez, R. V., & Goussous, N. (2025). Kidney transplantation using a pediatric en bloc graft after normothermic regional perfusion and donation after circulatory death procurement. Am J Transplant, 25(12), 2646–2650. https://doi.org/10.1016/j.ajt.2025.06.029
Howard, Brian, Mustafa S. Jundi, Douglas M. Overbey, Joseph W. Turek, Richard V. Perez, and Naeem Goussous. “Kidney transplantation using a pediatric en bloc graft after normothermic regional perfusion and donation after circulatory death procurement.Am J Transplant 25, no. 12 (December 2025): 2646–50. https://doi.org/10.1016/j.ajt.2025.06.029.
Howard B, Jundi MS, Overbey DM, Turek JW, Perez RV, Goussous N. Kidney transplantation using a pediatric en bloc graft after normothermic regional perfusion and donation after circulatory death procurement. Am J Transplant. 2025 Dec;25(12):2646–50.
Howard, Brian, et al. “Kidney transplantation using a pediatric en bloc graft after normothermic regional perfusion and donation after circulatory death procurement.Am J Transplant, vol. 25, no. 12, Dec. 2025, pp. 2646–50. Pubmed, doi:10.1016/j.ajt.2025.06.029.
Howard B, Jundi MS, Overbey DM, Turek JW, Perez RV, Goussous N. Kidney transplantation using a pediatric en bloc graft after normothermic regional perfusion and donation after circulatory death procurement. Am J Transplant. 2025 Dec;25(12):2646–2650.
Journal cover image

Published In

Am J Transplant

DOI

EISSN

1600-6143

Publication Date

December 2025

Volume

25

Issue

12

Start / End Page

2646 / 2650

Location

United States

Related Subject Headings

  • Tissue and Organ Procurement
  • Tissue Donors
  • Surgery
  • Prognosis
  • Perfusion
  • Organ Preservation
  • Male
  • Kidney Transplantation
  • Kidney Failure, Chronic
  • Infant