How To Interpret Subgroup Analyses from Prospective Randomized Clinical Trials: What Clinicians Need To Know.
Journal articles
- Editorial
Halabi, S; Guo, S
Published in: Eur Urol
January 2026
Subgroup analyses must be approached with caution. Only prespecified, well-powered analyses with formal interaction testing and validation can support strong claims; exploratory findings require confirmation. Integration of statistical rigor with clinical insight maximizes the value of subgroup analyses.
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Published In
Eur Urol
DOI
EISSN
1873-7560
Publication Date
January 2026
Volume
89
Issue
1
Start / End Page
1 / 4
Location
Switzerland
Related Subject Headings
- Urology & Nephrology
- Research Design
- Randomized Controlled Trials as Topic
- Prospective Studies
- Humans
- Data Interpretation, Statistical
- 3202 Clinical sciences
Citation
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ICMJE
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Halabi, S., & Guo, S. (2026). How To Interpret Subgroup Analyses from Prospective Randomized Clinical Trials: What Clinicians Need To Know. Eur Urol, 89(1), 1–4. https://doi.org/10.1016/j.eururo.2025.06.015
Halabi, Susan, and Siyuan Guo. “How To Interpret Subgroup Analyses from Prospective Randomized Clinical Trials: What Clinicians Need To Know.” Eur Urol 89, no. 1 (January 2026): 1–4. https://doi.org/10.1016/j.eururo.2025.06.015.
Halabi S, Guo S. How To Interpret Subgroup Analyses from Prospective Randomized Clinical Trials: What Clinicians Need To Know. Eur Urol. 2026 Jan;89(1):1–4.
Halabi, Susan, and Siyuan Guo. “How To Interpret Subgroup Analyses from Prospective Randomized Clinical Trials: What Clinicians Need To Know.” Eur Urol, vol. 89, no. 1, Jan. 2026, pp. 1–4. Pubmed, doi:10.1016/j.eururo.2025.06.015.
Halabi S, Guo S. How To Interpret Subgroup Analyses from Prospective Randomized Clinical Trials: What Clinicians Need To Know. Eur Urol. 2026 Jan;89(1):1–4.
Published In
Eur Urol
DOI
EISSN
1873-7560
Publication Date
January 2026
Volume
89
Issue
1
Start / End Page
1 / 4
Location
Switzerland
Related Subject Headings
- Urology & Nephrology
- Research Design
- Randomized Controlled Trials as Topic
- Prospective Studies
- Humans
- Data Interpretation, Statistical
- 3202 Clinical sciences