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Cervical Pedicle Inlet Screws: A Novel Trajectory for Navigated Sub-axial Cervical Screw Placement With Improved Biomechanical Characteristics Compared to Lateral Mass Screws.

Publication ,  Journal Article
Martin, CT; Bhowmick, DA; Rossi, V; Coric, D; Pham, MH; Schweitzer, A; Woods, D; Rawlinson, JJ
Published in: Global Spine J
July 8, 2025

Study DesignCadaveric Biomechanical.ObjectiveTo investigate the biomechanical characteristics of a new screw trajectory, which we have deemed the "pedicle inlet" trajectory.MethodsFour surgeons familiar with standard and image-guided cervical pedicle screw fixation techniques placed 3.5 mm diameter cervical fixation screws randomized at each sub-axial level to one of three fixation techniques: cervical pedicle, pedicle inlet, and lateral mass screw. A total of 180 screws were placed from C3 to C7 in 18 cadaveric spine samples. Maximal insertional torque was measured during the final seating of the screws. After confirmation of accuracy of screws with post-procedural CT-imaging, individual screws in the cadaveric samples were biomechanically tested for pull-out strength.ResultsAll screws were placed without breach into neurovascular spaces. The final insertional torque was equivalent (ANOVA, P > .05, 3.6 ± 1.7 Nm) across cervical pedicle screws, pedicle inlet, and lateral mass screws. Maximal pullout strength was observed for cervical pedicle screws (814.6 ± 387.3 N). Pedicle inlet screws had a 51% higher pullout strength as compared to lateral mass screws (593.2 ± 289.9 N v 392.4 ± 284.0 N, P < .01). All differences were statistically distinct from each other (ANOVA, P < .01).ConclusionsUse of image-guidance allows for safe placement along the pedicle inlet trajectory, with no recorded screw malposition, and a 51% improvement in pull out strength as compared to lateral mass screws. The pedicle inlet trajectory offers an alternative to traditional lateral mass screws with better fixation quality and may have particular application in percutaneous or minimally invasive posterior fusions.

Duke Scholars

Published In

Global Spine J

DOI

ISSN

2192-5682

Publication Date

July 8, 2025

Volume

16

Issue

1

Start / End Page

21925682251352439

Location

England

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

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ICMJE
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Martin, C. T., Bhowmick, D. A., Rossi, V., Coric, D., Pham, M. H., Schweitzer, A., … Rawlinson, J. J. (2025). Cervical Pedicle Inlet Screws: A Novel Trajectory for Navigated Sub-axial Cervical Screw Placement With Improved Biomechanical Characteristics Compared to Lateral Mass Screws. Global Spine J, 16(1), 21925682251352440. https://doi.org/10.1177/21925682251352439
Martin, Christopher T., Deb A. Bhowmick, Vincent Rossi, Domagoj Coric, Martin H. Pham, Amber Schweitzer, Daniel Woods, and Jeremy J. Rawlinson. “Cervical Pedicle Inlet Screws: A Novel Trajectory for Navigated Sub-axial Cervical Screw Placement With Improved Biomechanical Characteristics Compared to Lateral Mass Screws.Global Spine J 16, no. 1 (July 8, 2025): 21925682251352440. https://doi.org/10.1177/21925682251352439.
Martin CT, Bhowmick DA, Rossi V, Coric D, Pham MH, Schweitzer A, et al. Cervical Pedicle Inlet Screws: A Novel Trajectory for Navigated Sub-axial Cervical Screw Placement With Improved Biomechanical Characteristics Compared to Lateral Mass Screws. Global Spine J. 2025 Jul 8;16(1):21925682251352440.
Martin, Christopher T., et al. “Cervical Pedicle Inlet Screws: A Novel Trajectory for Navigated Sub-axial Cervical Screw Placement With Improved Biomechanical Characteristics Compared to Lateral Mass Screws.Global Spine J, vol. 16, no. 1, July 2025, p. 21925682251352440. Pubmed, doi:10.1177/21925682251352439.
Martin CT, Bhowmick DA, Rossi V, Coric D, Pham MH, Schweitzer A, Woods D, Rawlinson JJ. Cervical Pedicle Inlet Screws: A Novel Trajectory for Navigated Sub-axial Cervical Screw Placement With Improved Biomechanical Characteristics Compared to Lateral Mass Screws. Global Spine J. 2025 Jul 8;16(1):21925682251352440.
Journal cover image

Published In

Global Spine J

DOI

ISSN

2192-5682

Publication Date

July 8, 2025

Volume

16

Issue

1

Start / End Page

21925682251352439

Location

England

Related Subject Headings

  • 3202 Clinical sciences