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Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.

Publication ,  Journal Article
Prasad, M; Sandoval, GJ; Saade, GR; Hughes, BL; Clifton, RG; Reddy, UM; Bartholomew, A; Salazar, A; Chien, EK; Tita, ATN; Thorp, JM; Metz, TD ...
Published in: Clin Infect Dis
February 4, 2026

In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed.

Duke Scholars

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

February 4, 2026

Volume

81

Issue

6

Start / End Page

1102 / 1105

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • RNA, Viral
  • Pregnancy Complications, Infectious
  • Pregnancy
  • Polymerase Chain Reaction
  • Microbiology
  • Male
  • Infectious Disease Transmission, Vertical
  • Infant, Newborn
  • Infant
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Prasad, M., Sandoval, G. J., Saade, G. R., Hughes, B. L., Clifton, R. G., Reddy, U. M., … Macones, G. A. (2026). Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus. Clin Infect Dis, 81(6), 1102–1105. https://doi.org/10.1093/cid/ciaf266
Prasad, Mona, Grecio J. Sandoval, George R. Saade, Brenna L. Hughes, Rebecca G. Clifton, Uma M. Reddy, Anna Bartholomew, et al. “Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.Clin Infect Dis 81, no. 6 (February 4, 2026): 1102–5. https://doi.org/10.1093/cid/ciaf266.
Prasad M, Sandoval GJ, Saade GR, Hughes BL, Clifton RG, Reddy UM, et al. Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus. Clin Infect Dis. 2026 Feb 4;81(6):1102–5.
Prasad, Mona, et al. “Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.Clin Infect Dis, vol. 81, no. 6, Feb. 2026, pp. 1102–05. Pubmed, doi:10.1093/cid/ciaf266.
Prasad M, Sandoval GJ, Saade GR, Hughes BL, Clifton RG, Reddy UM, Bartholomew A, Salazar A, Chien EK, Tita ATN, Thorp JM, Metz TD, Wapner RJ, Sabharwal V, Simhan HN, Swamy GK, Heyborne KD, Sibai BM, Grobman WA, El-Sayed YY, Casey BM, Parry S, Macones GA. Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus. Clin Infect Dis. 2026 Feb 4;81(6):1102–1105.
Journal cover image

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

February 4, 2026

Volume

81

Issue

6

Start / End Page

1102 / 1105

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • RNA, Viral
  • Pregnancy Complications, Infectious
  • Pregnancy
  • Polymerase Chain Reaction
  • Microbiology
  • Male
  • Infectious Disease Transmission, Vertical
  • Infant, Newborn
  • Infant