On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death.
Publication
, Journal Article
Kucera, JA; Overbey, DM; Turek, JW
Published in: N Engl J Med
July 17, 2025
Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant deaths in this population. Donation after circulatory death (DCD) with normothermic regional perfusion has the potential to increase the donor pool by up to 30%. Ethical concerns have limited adoption of this technique in the United States and abroad. Consequently, a method facilitating ex vivo resuscitation of hearts from deceased donors after circulatory death (i.e., DCD hearts) is needed. We describe an on-table reanimation of a pediatric DCD heart transplanted into a 3-month-old recipient. Adverse events are reported.
Duke Scholars
Published In
N Engl J Med
DOI
EISSN
1533-4406
Publication Date
July 17, 2025
Volume
393
Issue
3
Start / End Page
275 / 280
Location
United States
Related Subject Headings
- Treatment Outcome
- Transplantation, Homologous
- Tissue and Organ Harvesting
- Tissue Donors
- Swine
- Perfusion
- Models, Animal
- Infant
- Humans
- Heart Transplantation
Citation
APA
Chicago
ICMJE
MLA
NLM
Kucera, J. A., Overbey, D. M., & Turek, J. W. (2025). On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death. N Engl J Med, 393(3), 275–280. https://doi.org/10.1056/NEJMoa2503487
Kucera, John A., Douglas M. Overbey, and Joseph W. Turek. “On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death.” N Engl J Med 393, no. 3 (July 17, 2025): 275–80. https://doi.org/10.1056/NEJMoa2503487.
Kucera JA, Overbey DM, Turek JW. On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death. N Engl J Med. 2025 Jul 17;393(3):275–80.
Kucera, John A., et al. “On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death.” N Engl J Med, vol. 393, no. 3, July 2025, pp. 275–80. Pubmed, doi:10.1056/NEJMoa2503487.
Kucera JA, Overbey DM, Turek JW. On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death. N Engl J Med. 2025 Jul 17;393(3):275–280.
Published In
N Engl J Med
DOI
EISSN
1533-4406
Publication Date
July 17, 2025
Volume
393
Issue
3
Start / End Page
275 / 280
Location
United States
Related Subject Headings
- Treatment Outcome
- Transplantation, Homologous
- Tissue and Organ Harvesting
- Tissue Donors
- Swine
- Perfusion
- Models, Animal
- Infant
- Humans
- Heart Transplantation