Endogenous human herpesviruses 6A/B.
Publication
, Journal Article
Flamand, L; Arbuckle, J; Bonnafous, P; Descamps, V; Hill, JA; Jarrett, R; Jerome, K; Kaufer, BB; Koide, R; Komaroff, AL; Medveczky, P; Mori, Y ...
Published in: Journal of virology
September 2025
Human herpesviruses 6A and 6B (HHV-6A/B) can integrate into the germline, resulting in inherited viral DNA-now proposed to be called "endogenous HHV-6A/B (eHHV-6A/B)." Present in 0.2-3% of humans, this integrated DNA is passed to offspring and may reactivate, posing health risks such as angina or lupus. To reduce confusion caused by varied terminology, researchers advocate using "eHHV-6A/B" for inherited forms and reserving "chromosomally integrated" for somatic integrations only.
Duke Scholars
Published In
Journal of virology
DOI
EISSN
1098-5514
ISSN
0022-538X
Publication Date
September 2025
Volume
99
Issue
9
Start / End Page
e0105425
Related Subject Headings
- Virus Integration
- Virology
- Roseolovirus Infections
- Humans
- Herpesvirus 6, Human
- DNA, Viral
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 30 Agricultural, veterinary and food sciences
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Flamand, L., Arbuckle, J., Bonnafous, P., Descamps, V., Hill, J. A., Jarrett, R., … Zerr, D. M. (2025). Endogenous human herpesviruses 6A/B. Journal of Virology, 99(9), e0105425. https://doi.org/10.1128/jvi.01054-25
Flamand, Louis, Jesse Arbuckle, Pascale Bonnafous, Vincent Descamps, Joshua A. Hill, Ruth Jarrett, Keith Jerome, et al. “Endogenous human herpesviruses 6A/B.” Journal of Virology 99, no. 9 (September 2025): e0105425. https://doi.org/10.1128/jvi.01054-25.
Flamand L, Arbuckle J, Bonnafous P, Descamps V, Hill JA, Jarrett R, et al. Endogenous human herpesviruses 6A/B. Journal of virology. 2025 Sep;99(9):e0105425.
Flamand, Louis, et al. “Endogenous human herpesviruses 6A/B.” Journal of Virology, vol. 99, no. 9, Sept. 2025, p. e0105425. Epmc, doi:10.1128/jvi.01054-25.
Flamand L, Arbuckle J, Bonnafous P, Descamps V, Hill JA, Jarrett R, Jerome K, Kaufer BB, Koide R, Komaroff AL, Medveczky P, Miura H, Mori Y, Parrish N, Pellett PE, Wood M, Yoshikawa T, Zerr DM. Endogenous human herpesviruses 6A/B. Journal of virology. 2025 Sep;99(9):e0105425.
Published In
Journal of virology
DOI
EISSN
1098-5514
ISSN
0022-538X
Publication Date
September 2025
Volume
99
Issue
9
Start / End Page
e0105425
Related Subject Headings
- Virus Integration
- Virology
- Roseolovirus Infections
- Humans
- Herpesvirus 6, Human
- DNA, Viral
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 30 Agricultural, veterinary and food sciences
- 11 Medical and Health Sciences