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Outcomes After Utilization of Autogenous Arm Vein Grafts for Lower Extremity Bypasses.

Publication ,  Journal Article
Loanzon, RS; Shafique, H; Cui, CL; Kim, Y; Williams, ZF
Published in: Ann Vasc Surg
December 2025

BACKGROUND: Lower extremity bypasses performed with autogernous conduit have superior patency and limb salvage. This is often performed with single segment great saphenous vein (GSV), but other options may be required for patients without available GSV. This study presents our experience utilizing arm veins as an alternative autogenous conduit for patients undergoing lower extremity bypass procedures. METHODS: A single-center retrospective study of patients at a Veterans Affairs Medical Center with peripheral arterial disease (PAD) who underwent lower extremity bypass with arm vein between January 2009 and July 2023 was performed. The primary outcomes were amputation-free survival (AFS) and major adverse limb event (MALE). Secondary outcomes include postoperative complications, such as postoperative surgical site infection, total hospital length of stay, 30-day mortality, and unplanned 30-day readmission. RESULTS: From January 2009 to June 2023, there were 42 lower extremity bypasses performed in patients who possessed inadequate GSV. All procedures were performed in men (n = 42, 100%). The median age was 67 years (interquartile range (IQR) 62-71 years). Nine procedures (21.4%) were performed for claudication, 21 (50%) for tissue loss, and 12 (28.6%) for rest pain. The majority involved bypassing to infrageniculate targets (n = 39, 93%). Conduit composition included single (n = 19, 45%), two-piece (n = 19, 45%), or three-piece (n = 4, 10%) composite grafts with arm vein. The median AFS was 3.86 years (IQR 1.19-6.65 years). Five patients required major amputation (15.6%). The median time to MALE was 0.88 years (IQR 0.23-1.69 years). Overall, 30-day mortality was 2.4% (n = 1). Postoperative complications included surgical site infection in 9 patients (21.4%), hematoma in 3 patients (7.1%), early graft thrombosis in one patient (2.4%), wound dehiscence in one patient (2.4%), and a lymph leak in one patient (2.4%). The median length of stay was 6 days (IQR 3.3-9.5 days). CONCLUSION: Arm vein is a viable alternative autogenous conduit for lower extremity arterial bypasses in patients without adequate GSV.

Duke Scholars

Published In

Ann Vasc Surg

DOI

EISSN

1615-5947

Publication Date

December 2025

Volume

121

Start / End Page

399 / 405

Location

Netherlands

Related Subject Headings

  • Veins
  • Vascular Patency
  • Vascular Grafting
  • Treatment Outcome
  • Transplantation, Autologous
  • Time Factors
  • Saphenous Vein
  • Risk Factors
  • Risk Assessment
  • Retrospective Studies
 

Citation

APA
Chicago
ICMJE
MLA
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Loanzon, R. S., Shafique, H., Cui, C. L., Kim, Y., & Williams, Z. F. (2025). Outcomes After Utilization of Autogenous Arm Vein Grafts for Lower Extremity Bypasses. Ann Vasc Surg, 121, 399–405. https://doi.org/10.1016/j.avsg.2025.07.039
Loanzon, Roberto S., Hana Shafique, Christina L. Cui, Young Kim, and Zachary F. Williams. “Outcomes After Utilization of Autogenous Arm Vein Grafts for Lower Extremity Bypasses.Ann Vasc Surg 121 (December 2025): 399–405. https://doi.org/10.1016/j.avsg.2025.07.039.
Loanzon RS, Shafique H, Cui CL, Kim Y, Williams ZF. Outcomes After Utilization of Autogenous Arm Vein Grafts for Lower Extremity Bypasses. Ann Vasc Surg. 2025 Dec;121:399–405.
Loanzon, Roberto S., et al. “Outcomes After Utilization of Autogenous Arm Vein Grafts for Lower Extremity Bypasses.Ann Vasc Surg, vol. 121, Dec. 2025, pp. 399–405. Pubmed, doi:10.1016/j.avsg.2025.07.039.
Loanzon RS, Shafique H, Cui CL, Kim Y, Williams ZF. Outcomes After Utilization of Autogenous Arm Vein Grafts for Lower Extremity Bypasses. Ann Vasc Surg. 2025 Dec;121:399–405.
Journal cover image

Published In

Ann Vasc Surg

DOI

EISSN

1615-5947

Publication Date

December 2025

Volume

121

Start / End Page

399 / 405

Location

Netherlands

Related Subject Headings

  • Veins
  • Vascular Patency
  • Vascular Grafting
  • Treatment Outcome
  • Transplantation, Autologous
  • Time Factors
  • Saphenous Vein
  • Risk Factors
  • Risk Assessment
  • Retrospective Studies