Infection Prevention Approaches for Clostridioides difficile.

Clostridioides difficile prevention is challenging as spores are highly resilient and transmission sources diverse. Hand hygiene, contact precautions, and environmental decontamination are fundamental infection prevention strategies. Antimicrobial stewardship is highly effective at reducing C difficile risk at both the individual and institutional level. Supplemental control measures such as no-touch disinfection technologies and screening/isolation of carriers are generally reserved for situations in which fundamental control measures prove insufficient. Reducing host vulnerability through immunization, prophylactic antibiotics directed against C difficile, or products that protect/augment the microbiome may offer promise in the future.

Duke Scholars

Author Nicholas Turner Medicine, Infectious Diseases