Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression.
Publication
, Journal Article
Puviindran, BJ; Wallace, S; Ayasoufi, K; Lerner, E; Fecci, PE
Published in: Neurooncol Adv
September 2025
Immunotherapies have thus far proved of limited efficacy against glioblastoma. Failures can be attributed to a host of immunosuppressive mechanisms that are either directly employed by the tumor or are instead a convenient feature of the intracranial environment. This review aims to categorize glioblastoma immune-evasive tendencies, provide an update on our understanding of etiologies, and describe newer approaches to improving therapeutic responses.
Duke Scholars
Published In
Neurooncol Adv
DOI
EISSN
2632-2498
Publication Date
September 2025
Volume
7
Issue
Suppl 4
Start / End Page
iv4 / iv18
Location
England
Citation
APA
Chicago
ICMJE
MLA
NLM
Puviindran, B. J., Wallace, S., Ayasoufi, K., Lerner, E., & Fecci, P. E. (2025). Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression. Neurooncol Adv, 7(Suppl 4), iv4–iv18. https://doi.org/10.1093/noajnl/vdaf006
Puviindran, Bhairavy J., Shannon Wallace, Katayoun Ayasoufi, Emily Lerner, and Peter E. Fecci. “Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression.” Neurooncol Adv 7, no. Suppl 4 (September 2025): iv4–18. https://doi.org/10.1093/noajnl/vdaf006.
Puviindran BJ, Wallace S, Ayasoufi K, Lerner E, Fecci PE. Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression. Neurooncol Adv. 2025 Sep;7(Suppl 4):iv4–18.
Puviindran, Bhairavy J., et al. “Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression.” Neurooncol Adv, vol. 7, no. Suppl 4, Sept. 2025, pp. iv4–18. Pubmed, doi:10.1093/noajnl/vdaf006.
Puviindran BJ, Wallace S, Ayasoufi K, Lerner E, Fecci PE. Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression. Neurooncol Adv. 2025 Sep;7(Suppl 4):iv4–iv18.
Published In
Neurooncol Adv
DOI
EISSN
2632-2498
Publication Date
September 2025
Volume
7
Issue
Suppl 4
Start / End Page
iv4 / iv18
Location
England