Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression.
Journal articles
- Journal Article, Review
Puviindran, BJ; Wallace, S; Ayasoufi, K; Lerner, E; Fecci, PE
Published in: Neurooncol Adv
September 2025
Immunotherapies have thus far proved of limited efficacy against glioblastoma. Failures can be attributed to a host of immunosuppressive mechanisms that are either directly employed by the tumor or are instead a convenient feature of the intracranial environment. This review aims to categorize glioblastoma immune-evasive tendencies, provide an update on our understanding of etiologies, and describe newer approaches to improving therapeutic responses.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Neurooncol Adv
DOI
EISSN
2632-2498
Publication Date
September 2025
Volume
7
Issue
Suppl 4
Start / End Page
iv4 / iv18
Location
England
Citation
APA
Chicago
ICMJE
MLA
NLM
Puviindran, B. J., Wallace, S., Ayasoufi, K., Lerner, E., & Fecci, P. E. (2025). Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression. Neurooncol Adv, 7(Suppl 4), iv4–iv18. https://doi.org/10.1093/noajnl/vdaf006
Puviindran, Bhairavy J., Shannon Wallace, Katayoun Ayasoufi, Emily Lerner, and Peter E. Fecci. “Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression.” Neurooncol Adv 7, no. Suppl 4 (September 2025): iv4–18. https://doi.org/10.1093/noajnl/vdaf006.
Puviindran BJ, Wallace S, Ayasoufi K, Lerner E, Fecci PE. Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression. Neurooncol Adv. 2025 Sep;7(Suppl 4):iv4–18.
Puviindran, Bhairavy J., et al. “Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression.” Neurooncol Adv, vol. 7, no. Suppl 4, Sept. 2025, pp. iv4–18. Pubmed, doi:10.1093/noajnl/vdaf006.
Puviindran BJ, Wallace S, Ayasoufi K, Lerner E, Fecci PE. Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression. Neurooncol Adv. 2025 Sep;7(Suppl 4):iv4–iv18.
Published In
Neurooncol Adv
DOI
EISSN
2632-2498
Publication Date
September 2025
Volume
7
Issue
Suppl 4
Start / End Page
iv4 / iv18
Location
England