Skip to main content
Journal cover image

Qualitative Analysis of Patient-Physician Discussions About the Benefits and Tradeoffs of Heart Failure Medications.

Publication ,  Journal Article
Biermann, HD; Speight, CD; Montembeau, SC; Mitchell, AR; Lowe, EF; Krishnan, A; Scherer, LD; Matlock, DD; Ubel, PA; Allen, LA; Dickert, NW
Published in: Journal of cardiac failure
September 2025

How physicians frame medication benefits and tradeoffs while engaging in shared decision-making with patients is not well described in the management of heart failure with reduced ejection fraction (HFrEF).This qualitative, secondary analysis of recorded encounters between clinicians and patients with HFrEF sought to identify major themes regarding the communication of medication benefits and tradeoffs. Encounters occurred in 6 clinics within 2 academic health systems. English-speaking adult patients with a diagnosis of HFrEF (ejection fraction ≤40%) were enrolled.A total of 247 patient encounters were analyzed. Patients' mean (standard deviation) age was 62.9 (13.9) years; 70.5% were male; 64.0% were White, 26.3% Black, and 3.2% Hispanic/Latinx. Overall, 70% of encounters contained a discussion involving medication benefits. Substantial variability was observed, and 4 main themes emerged. (1) Primary benefits (increased survival, reduced hospitalizations, better quality of life) were commonly discussed, but clinicians described the magnitude in only 2 cases. (2) Adjunctive drug benefits (improved physiology, tolerability, affordability) were described nonspecifically. (3) Persuasive forms of communication were common, including direct appeals to authority/guidelines, references to pharmaceutical advertisements, and emotive language. (4) Significant heterogeneity was present in the content and character of benefit tradeoff discussions.Rare inclusion of medication benefit magnitude, variability in the presentation of benefits, and use of persuasive and emotive communication all challenge traditional notions of shared decision-making but are commonly encountered in clinical interactions for heart failure. Recognizing these contextual factors and evaluating which are consistent with effective decision-making in HFrEF and other chronic conditions is important and needed.

Duke Scholars

Published In

Journal of cardiac failure

DOI

EISSN

1532-8414

ISSN

1071-9164

Publication Date

September 2025

Start / End Page

S1071-9164(25)00375-6

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1110 Nursing
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Biermann, H. D., Speight, C. D., Montembeau, S. C., Mitchell, A. R., Lowe, E. F., Krishnan, A., … Dickert, N. W. (2025). Qualitative Analysis of Patient-Physician Discussions About the Benefits and Tradeoffs of Heart Failure Medications. Journal of Cardiac Failure, S1071-9164(25)00375-6. https://doi.org/10.1016/j.cardfail.2025.07.025
Biermann, Henry D., Candace D. Speight, Sarah C. Montembeau, Andrea R. Mitchell, Emily F. Lowe, Advaita Krishnan, Laura D. Scherer, et al. “Qualitative Analysis of Patient-Physician Discussions About the Benefits and Tradeoffs of Heart Failure Medications.Journal of Cardiac Failure, September 2025, S1071-9164(25)00375-6. https://doi.org/10.1016/j.cardfail.2025.07.025.
Biermann HD, Speight CD, Montembeau SC, Mitchell AR, Lowe EF, Krishnan A, et al. Qualitative Analysis of Patient-Physician Discussions About the Benefits and Tradeoffs of Heart Failure Medications. Journal of cardiac failure. 2025 Sep;S1071-9164(25)00375-6.
Biermann, Henry D., et al. “Qualitative Analysis of Patient-Physician Discussions About the Benefits and Tradeoffs of Heart Failure Medications.Journal of Cardiac Failure, Sept. 2025, pp. S1071-9164(25)00375-6. Epmc, doi:10.1016/j.cardfail.2025.07.025.
Biermann HD, Speight CD, Montembeau SC, Mitchell AR, Lowe EF, Krishnan A, Scherer LD, Matlock DD, Ubel PA, Allen LA, Dickert NW. Qualitative Analysis of Patient-Physician Discussions About the Benefits and Tradeoffs of Heart Failure Medications. Journal of cardiac failure. 2025 Sep;S1071-9164(25)00375–6.
Journal cover image

Published In

Journal of cardiac failure

DOI

EISSN

1532-8414

ISSN

1071-9164

Publication Date

September 2025

Start / End Page

S1071-9164(25)00375-6

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1110 Nursing
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology