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Time To Tighten Up on Prehospital Tourniquets: An EAST Multicenter Trial of Prehospital Procedures in Penetrating Trauma Shows No Benefit With Current Tourniquet Practices for Extremity Trauma in Urban Settings.

Publication ,  Journal Article
Taghavi, S; Simpson, JT; Ali, A; Nordham, KD; Tatebe, LC; Haut, ER; Anderson, C; Salib, N; Maher, Z; Goldberg, AJ; Raza, S; Chang, G; Bird, E ...
Published in: Am Surg
October 17, 2025

BackgroundPrehospital tourniquet (PHT) use has become widespread. However, whether it improves outcomes after penetrating proximal extremity trauma in urban settings remains unknown. We hypothesized that PHT improves mortality in this setting.Materials and MethodsThis was a post hoc analysis of a multicenter study of adults (18+ years) with penetrating torso and/or proximal extremity trauma from 25 urban trauma centers. Subjects were allocated via nearest neighbor propensity matching (chest, abdominal, or extremity injury, GSW vs stab, and vascular injuries) to compare similarly-injured PHT and non-PHT patients.ResultsAmong 2352 patients, 117 (4.9%) received PHT. Prehospital tourniquet patients had 22 (18.84%) arterial injuries, 8 (6.8%) venous injuries, and 92 (78.6%) non-vascular injuries. Most PHTs (86, 73.5%) were placed on-scene, and 22 (18.8%) en-route. Admission of systolic blood pressure was not different between PHT and non-PHT patients. Prehospital tourniquet did not impact survival on regression analysis. After propensity matching, 218 patients remained, who were primarily male (n = 182, 83.9%) with median (IQR) age 30 (23-39) years and new injury severity score 9 (3-17). Mortality was similar between PHT and non-PHT groups (6.4% vs 7.3%; P = 1.0). Matched comparison of patients with vascular injury showed similar mortality for PHT vs non-PHT (3.7% vs 3.7%, P = 1.00). The same was true for isolated extremity trauma (4.1% vs 0.0%, P = 0.25).ConclusionsPHT use for urban, penetrating proximal extremity trauma was not associated with decreased mortality or complications. Further research may determine whether modified tourniquet training improves outcomes, or whether immediate transport to a trauma center is more beneficial for these patients.

Duke Scholars

Published In

Am Surg

DOI

EISSN

1555-9823

Publication Date

October 17, 2025

Start / End Page

31348251388954

Location

United States

Related Subject Headings

  • Surgery
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Taghavi, S., Simpson, J. T., Ali, A., Nordham, K. D., Tatebe, L. C., Haut, E. R., … Tatum, D. (2025). Time To Tighten Up on Prehospital Tourniquets: An EAST Multicenter Trial of Prehospital Procedures in Penetrating Trauma Shows No Benefit With Current Tourniquet Practices for Extremity Trauma in Urban Settings. Am Surg, 31348251388954. https://doi.org/10.1177/00031348251388954
Taghavi, Sharven, John T. Simpson, Ayman Ali, Kristen D. Nordham, Leah C. Tatebe, Elliot R. Haut, Christofer Anderson, et al. “Time To Tighten Up on Prehospital Tourniquets: An EAST Multicenter Trial of Prehospital Procedures in Penetrating Trauma Shows No Benefit With Current Tourniquet Practices for Extremity Trauma in Urban Settings.Am Surg, October 17, 2025, 31348251388954. https://doi.org/10.1177/00031348251388954.
Taghavi S, Simpson JT, Ali A, Nordham KD, Tatebe LC, Haut ER, Anderson C, Salib N, Maher Z, Goldberg AJ, Raza S, Chang G, Toraih E, Mendiola Pla M, Ninokawa S, Maluso P, Keating J, Burruss S, Reeves M, Coleman LE, Shatz DV, Goldenberg Sandau A, Bhupathi A, Spalding MC, LaRiccia A, Bird E, Noorbakhsh MR, Babowice J, Nelson MC, Jacobson LE, Williams J, Hayward TZ, Holler E, Lieser MJ, Berne JD, Mederos DR, Askari R, Okafor B, Etchill E, Fang R, Roche SL, Whittenburg L, Bernard AC, Haan JM, Lightwine KL, Norwood SH, Murry J, Gamber MA, Carrick MM, Bugaev N, Tatar A, Tatum D. Time To Tighten Up on Prehospital Tourniquets: An EAST Multicenter Trial of Prehospital Procedures in Penetrating Trauma Shows No Benefit With Current Tourniquet Practices for Extremity Trauma in Urban Settings. Am Surg. 2025 Oct 17;31348251388954.

Published In

Am Surg

DOI

EISSN

1555-9823

Publication Date

October 17, 2025

Start / End Page

31348251388954

Location

United States

Related Subject Headings

  • Surgery
  • 3202 Clinical sciences
  • 1103 Clinical Sciences