A roadmap to precision medicine through post-genomic electronic medical records.
Publication
, Journal Article
Mendez, KM; Reinke, SN; Kelly, RS; Chen, Q; Su, M; McGeachie, M; Weiss, S; Broadhurst, DI; Lasky-Su, JA
Published in: Nature communications
February 2025
The promise of integrating Electronic Medical Records (EMR) and genetic data for precision medicine has largely fallen short due to its omission of environmental context over time. Post-genomic data can bridge this gap by capturing the real-time dynamic relationship between underlying genetics and the environment. This perspective highlights the pivotal role of integrating EMR and post-genomics for personalized health, reflecting on lessons from past efforts, and outlining a roadmap of challenges and opportunities that must be addressed to realize the potential of precision medicine.
Duke Scholars
Published In
Nature communications
DOI
EISSN
2041-1723
ISSN
2041-1723
Publication Date
February 2025
Volume
16
Issue
1
Start / End Page
1700
Related Subject Headings
- Precision Medicine
- Humans
- Genomics
- Electronic Health Records
Citation
APA
Chicago
ICMJE
MLA
NLM
Mendez, K. M., Reinke, S. N., Kelly, R. S., Chen, Q., Su, M., McGeachie, M., … Lasky-Su, J. A. (2025). A roadmap to precision medicine through post-genomic electronic medical records. Nature Communications, 16(1), 1700. https://doi.org/10.1038/s41467-025-56442-4
Mendez, Kevin M., Stacey N. Reinke, Rachel S. Kelly, Qingwen Chen, Mark Su, Michael McGeachie, Scott Weiss, David I. Broadhurst, and Jessica A. Lasky-Su. “A roadmap to precision medicine through post-genomic electronic medical records.” Nature Communications 16, no. 1 (February 2025): 1700. https://doi.org/10.1038/s41467-025-56442-4.
Mendez KM, Reinke SN, Kelly RS, Chen Q, Su M, McGeachie M, et al. A roadmap to precision medicine through post-genomic electronic medical records. Nature communications. 2025 Feb;16(1):1700.
Mendez, Kevin M., et al. “A roadmap to precision medicine through post-genomic electronic medical records.” Nature Communications, vol. 16, no. 1, Feb. 2025, p. 1700. Epmc, doi:10.1038/s41467-025-56442-4.
Mendez KM, Reinke SN, Kelly RS, Chen Q, Su M, McGeachie M, Weiss S, Broadhurst DI, Lasky-Su JA. A roadmap to precision medicine through post-genomic electronic medical records. Nature communications. 2025 Feb;16(1):1700.
Published In
Nature communications
DOI
EISSN
2041-1723
ISSN
2041-1723
Publication Date
February 2025
Volume
16
Issue
1
Start / End Page
1700
Related Subject Headings
- Precision Medicine
- Humans
- Genomics
- Electronic Health Records