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Neonatal Choledocholithiasis: A Rare but Challenging Surgical Scenario.

Publication ,  Journal Article
Singh, ES; Lopez-Flores, R; Thornton, S; Chen, F; Sudan, D; Vikraman Sushama, D; Fitzgerald, T; Greenwald, E
Published in: Cureus
September 2025

Choledocholithiasis is a rare diagnosis in neonates, and there are no standard management guidelines for this population. Additionally, endoscopic retrograde cholangiopancreatography (ERCP) is often not an option due to the small size of the common bile duct and non-availability of appropriately sized neonatal endoscopes. We present the cases of two neonates with choledocholithiasis. Both patients underwent open cholecystectomy with common bile duct exploration. The biliary stones were not removable, and therefore both underwent a Roux-en-Y hepaticojejunostomy. Both neonates have done well postoperatively. While hyperbilirubinemia is common in neonates, choledocholithiasis is challenging to diagnose. Diagnosis requires a broad differential and the use of abdominal ultrasound. While ERCP is the gold standard in adults, it is difficult to perform in neonates. Therefore, other treatment modalities involving laparoscopic and open surgery may be necessary. There is a need for improved management guidelines and endoscopic treatment options for neonates with choledocholithiasis.

Duke Scholars

Published In

Cureus

DOI

ISSN

2168-8184

Publication Date

September 2025

Volume

17

Issue

9

Start / End Page

e93518

Location

United States

Related Subject Headings

  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Singh, E. S., Lopez-Flores, R., Thornton, S., Chen, F., Sudan, D., Vikraman Sushama, D., … Greenwald, E. (2025). Neonatal Choledocholithiasis: A Rare but Challenging Surgical Scenario. Cureus, 17(9), e93518. https://doi.org/10.7759/cureus.93518
Singh, Eden S., Ruby Lopez-Flores, Steven Thornton, Fengming Chen, Debra Sudan, Deepak Vikraman Sushama, Tamara Fitzgerald, and Emily Greenwald. “Neonatal Choledocholithiasis: A Rare but Challenging Surgical Scenario.Cureus 17, no. 9 (September 2025): e93518. https://doi.org/10.7759/cureus.93518.
Singh ES, Lopez-Flores R, Thornton S, Chen F, Sudan D, Vikraman Sushama D, et al. Neonatal Choledocholithiasis: A Rare but Challenging Surgical Scenario. Cureus. 2025 Sep;17(9):e93518.
Singh, Eden S., et al. “Neonatal Choledocholithiasis: A Rare but Challenging Surgical Scenario.Cureus, vol. 17, no. 9, Sept. 2025, p. e93518. Pubmed, doi:10.7759/cureus.93518.
Singh ES, Lopez-Flores R, Thornton S, Chen F, Sudan D, Vikraman Sushama D, Fitzgerald T, Greenwald E. Neonatal Choledocholithiasis: A Rare but Challenging Surgical Scenario. Cureus. 2025 Sep;17(9):e93518.

Published In

Cureus

DOI

ISSN

2168-8184

Publication Date

September 2025

Volume

17

Issue

9

Start / End Page

e93518

Location

United States

Related Subject Headings

  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences