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Moral, Religious, or Spiritual Problem: An Expanded Z Code Diagnostic Category in the DSM-5-TR.

Publication ,  Journal Article
Mattson, S; VanderWeele, TJ; Lu, F; Carey, LB; Cowden, RG; Fung, EN; Koenig, HG; Peteet, J; Wortham, J
Published in: J Nerv Ment Dis
November 1, 2025

INTRODUCTION: The DSM has made advances in helping clinicians address cultural factors important in psychiatric care, including the acknowledgement of religious and spiritual problems that impact a patient's mental health. However, moral problems have been under-recognized as a culturally contextualized source of negative consequences for occupational, social, and other areas of functioning. METHODS: To recognize the clinical significance of moral problems, an expanded DSM Z-code diagnostic category entitled "Moral, Religious, or Spiritual Problem" was recently approved. RESULTS: In light of this development, this paper reviews the conceptual and empirical connections with regard to moral, religious, and spiritual problems. A definition of moral problems is presented in relationship to transgressions of an individual's moral identity, which may include moral dilemmas, moral distress, and moral injury. CONCLUSIONS: Various differential diagnostic issues are raised related to this expanded Z-code, as well as potential implications for clinical practice, public health, and future research.

Duke Scholars

Published In

J Nerv Ment Dis

DOI

EISSN

1539-736X

Publication Date

November 1, 2025

Volume

213

Issue

11

Start / End Page

297 / 304

Location

United States

Related Subject Headings

  • Spirituality
  • Religion and Psychology
  • Psychiatry
  • Morals
  • Mental Disorders
  • Humans
  • Diagnostic and Statistical Manual of Mental Disorders
  • 5203 Clinical and health psychology
  • 3202 Clinical sciences
  • 1702 Cognitive Sciences
 

Citation

APA
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Mattson, S., VanderWeele, T. J., Lu, F., Carey, L. B., Cowden, R. G., Fung, E. N., … Wortham, J. (2025). Moral, Religious, or Spiritual Problem: An Expanded Z Code Diagnostic Category in the DSM-5-TR. J Nerv Ment Dis, 213(11), 297–304. https://doi.org/10.1097/NMD.0000000000001856
Mattson, Seth, Tyler J. VanderWeele, Francis Lu, Lindsay B. Carey, Richard G. Cowden, Eric N. Fung, Harold G. Koenig, John Peteet, and Jennifer Wortham. “Moral, Religious, or Spiritual Problem: An Expanded Z Code Diagnostic Category in the DSM-5-TR.J Nerv Ment Dis 213, no. 11 (November 1, 2025): 297–304. https://doi.org/10.1097/NMD.0000000000001856.
Mattson S, VanderWeele TJ, Lu F, Carey LB, Cowden RG, Fung EN, et al. Moral, Religious, or Spiritual Problem: An Expanded Z Code Diagnostic Category in the DSM-5-TR. J Nerv Ment Dis. 2025 Nov 1;213(11):297–304.
Mattson, Seth, et al. “Moral, Religious, or Spiritual Problem: An Expanded Z Code Diagnostic Category in the DSM-5-TR.J Nerv Ment Dis, vol. 213, no. 11, Nov. 2025, pp. 297–304. Pubmed, doi:10.1097/NMD.0000000000001856.
Mattson S, VanderWeele TJ, Lu F, Carey LB, Cowden RG, Fung EN, Koenig HG, Peteet J, Wortham J. Moral, Religious, or Spiritual Problem: An Expanded Z Code Diagnostic Category in the DSM-5-TR. J Nerv Ment Dis. 2025 Nov 1;213(11):297–304.

Published In

J Nerv Ment Dis

DOI

EISSN

1539-736X

Publication Date

November 1, 2025

Volume

213

Issue

11

Start / End Page

297 / 304

Location

United States

Related Subject Headings

  • Spirituality
  • Religion and Psychology
  • Psychiatry
  • Morals
  • Mental Disorders
  • Humans
  • Diagnostic and Statistical Manual of Mental Disorders
  • 5203 Clinical and health psychology
  • 3202 Clinical sciences
  • 1702 Cognitive Sciences