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Acupuncture for acute musculoskeletal pain in the emergency department and clinic: a pragmatic randomized trial.

Journal articles  - Journal Article, Pragmatic Clinical Trial
Eucker, SA; Glass, O; Knisely, MR; O'Regan, A; De Larco, C; Mill, M; Dixon, A; Sill Henis, M; Walker, E; Gordee, A; Chow, S-C; Kuchibhatla, M
Published in: Pain Med
May 1, 2026

BACKGROUND: cute musculoskeletal pain in emergency department (ED) patients is challenging to treat with medications alone, but adding acupuncture may improve pain outcomes. METHODS: In this pragmatic randomized controlled trial, acupuncture was delivered by licensed acupuncturists in the ED and twice a week in follow-up clinic for 1 month. From February 10, 2020 to April 19, 2023, 2781 adult patients at an academic ED with acute (≤7 days) musculoskeletal pain in neck, back and/or extremities were screened, and 599 were enrolled and randomized to usual care only (n = 189, 31.6%) or acupuncture plus usual care (n = 410, 68.4%). RESULTS: Acupuncture and control arms had similar demographics (mean age 45.2, SD 15.8; 57.7% female) and baseline pain scores (control 7.1, SD 2.2; acupuncture 7.1, SD 2.3). At 1 month, pain scores were similar between arms (control 3.8, SD 3.2; acupuncture 3.2, SD 3.0). However, 178 (43.4%) participants in the acupuncture arm were unable to attend acupuncture clinic and reported time and financial constraints. Exploratory analysis of pain score by number of clinic sessions attended showed that patients attending 6 or more acupuncture sessions (n = 121, 20.2%) experienced significant pain improvements compared to those with fewer sessions (n = 478, 79.8%). CONCLUSION: Improving access and availability of acupuncture in outpatient settings may be needed for more effective pain management.

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Published In

Pain Med

DOI

EISSN

1526-4637

Publication Date

May 1, 2026

Volume

27

Issue

5

Start / End Page

525 / 533

Location

England

Related Subject Headings

  • Treatment Outcome
  • Pain Measurement
  • Pain Management
  • Musculoskeletal Pain
  • Middle Aged
  • Male
  • Humans
  • Female
  • Emergency Service, Hospital
  • Anesthesiology
 

Citation

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Eucker, S. A., Glass, O., Knisely, M. R., O’Regan, A., De Larco, C., Mill, M., … Kuchibhatla, M. (2026). Acupuncture for acute musculoskeletal pain in the emergency department and clinic: a pragmatic randomized trial. Pain Med, 27(5), 525–533. https://doi.org/10.1093/pm/pnaf165
Eucker, Stephanie A., Oliver Glass, Mitchell R. Knisely, Amy O’Regan, Christi De Larco, Michelle Mill, Austin Dixon, et al. “Acupuncture for acute musculoskeletal pain in the emergency department and clinic: a pragmatic randomized trial.Pain Med 27, no. 5 (May 1, 2026): 525–33. https://doi.org/10.1093/pm/pnaf165.
Eucker SA, Glass O, Knisely MR, O’Regan A, De Larco C, Mill M, et al. Acupuncture for acute musculoskeletal pain in the emergency department and clinic: a pragmatic randomized trial. Pain Med. 2026 May 1;27(5):525–33.
Eucker, Stephanie A., et al. “Acupuncture for acute musculoskeletal pain in the emergency department and clinic: a pragmatic randomized trial.Pain Med, vol. 27, no. 5, May 2026, pp. 525–33. Pubmed, doi:10.1093/pm/pnaf165.
Eucker SA, Glass O, Knisely MR, O’Regan A, De Larco C, Mill M, Dixon A, Sill Henis M, Walker E, Gordee A, Chow S-C, Kuchibhatla M. Acupuncture for acute musculoskeletal pain in the emergency department and clinic: a pragmatic randomized trial. Pain Med. 2026 May 1;27(5):525–533.
Journal cover image

Published In

Pain Med

DOI

EISSN

1526-4637

Publication Date

May 1, 2026

Volume

27

Issue

5

Start / End Page

525 / 533

Location

England

Related Subject Headings

  • Treatment Outcome
  • Pain Measurement
  • Pain Management
  • Musculoskeletal Pain
  • Middle Aged
  • Male
  • Humans
  • Female
  • Emergency Service, Hospital
  • Anesthesiology