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Acupuncture for Acute Musculoskeletal Pain in the Emergency Department and Clinic: A Pragmatic Randomized Trial.

Publication ,  Journal Article
Eucker, SA; Glass, O; Knisely, MR; O'Regan, A; De Larco, C; Mill, M; Dixon, A; Sill Henis, M; Walker, E; Gordee, A; Chow, S-C; Kuchibhatla, M
Published in: Pain Med
December 1, 2025

BACKGROUND: Acute musculoskeletal pain in emergency department (ED) patients is challenging to treat with medications alone, but adding acupuncture may improve pain outcomes. METHODS: In this pragmatic randomized controlled trial, acupuncture was delivered by licensed acupuncturists in the ED and twice a week in follow-up clinic for 1 month. From February 10, 2020 to April 19, 2023, 2781 adult patients at an academic ED with acute (≤7 days) musculoskeletal pain in neck, back and/or extremities were screened, and 599 were enrolled and randomized to usual care only (n = 189, 31.6%) or acupuncture plus usual care (n = 410, 68.4%). RESULTS: Acupuncture and control arms had similar demographics (mean age 45.2, SD 15.8; 57.7% female) and baseline pain scores (control 7.1, SD 2.2; acupuncture 7.1, SD 2.3). At 1 month, pain scores were similar between arms (control 3.8, SD 3.2; acupuncture 3.2, SD 3.0). However, 178 (43.4%) participants in the acupuncture arm were unable to attend acupuncture clinic and reported time and financial constraints. Exploratory analysis of pain score by number of clinic sessions attended showed that patients attending 6 or more acupuncture sessions (n = 121, 20.2%) experienced significant pain improvements compared to those with fewer sessions (n = 478, 79.8%). CONCLUSION: Improving access and availability of acupuncture in outpatient settings may be needed for more effective pain management.

Duke Scholars

Published In

Pain Med

DOI

EISSN

1526-4637

Publication Date

December 1, 2025

Location

England

Related Subject Headings

  • Anesthesiology
  • 5203 Clinical and health psychology
  • 4203 Health services and systems
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 1103 Clinical Sciences
 

Citation

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Eucker, S. A., Glass, O., Knisely, M. R., O’Regan, A., De Larco, C., Mill, M., … Kuchibhatla, M. (2025). Acupuncture for Acute Musculoskeletal Pain in the Emergency Department and Clinic: A Pragmatic Randomized Trial. Pain Med. https://doi.org/10.1093/pm/pnaf165
Eucker, Stephanie A., Oliver Glass, Mitchell R. Knisely, Amy O’Regan, Christi De Larco, Michelle Mill, Austin Dixon, et al. “Acupuncture for Acute Musculoskeletal Pain in the Emergency Department and Clinic: A Pragmatic Randomized Trial.Pain Med, December 1, 2025. https://doi.org/10.1093/pm/pnaf165.
Eucker SA, Glass O, Knisely MR, O’Regan A, De Larco C, Mill M, et al. Acupuncture for Acute Musculoskeletal Pain in the Emergency Department and Clinic: A Pragmatic Randomized Trial. Pain Med. 2025 Dec 1;
Eucker, Stephanie A., et al. “Acupuncture for Acute Musculoskeletal Pain in the Emergency Department and Clinic: A Pragmatic Randomized Trial.Pain Med, Dec. 2025. Pubmed, doi:10.1093/pm/pnaf165.
Eucker SA, Glass O, Knisely MR, O’Regan A, De Larco C, Mill M, Dixon A, Sill Henis M, Walker E, Gordee A, Chow S-C, Kuchibhatla M. Acupuncture for Acute Musculoskeletal Pain in the Emergency Department and Clinic: A Pragmatic Randomized Trial. Pain Med. 2025 Dec 1;
Journal cover image

Published In

Pain Med

DOI

EISSN

1526-4637

Publication Date

December 1, 2025

Location

England

Related Subject Headings

  • Anesthesiology
  • 5203 Clinical and health psychology
  • 4203 Health services and systems
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 1103 Clinical Sciences