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A modified Delphi consensus on periprosthetic infection in orthopaedic oncology : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

Publication ,  Journal Article
Jeys, L; Botello, E; Boyle, RA; Ebeid, W; Houdek, MT; Kurisunkal, VJ; Morgan-Jones, R; Morris, GV; Puri, A; Ruggieri, P; Laitinen, MK; Ae, K ...
Published in: Bone Joint J
December 1, 2025

AIMS: The aim of this study was to achieve consensus for important topics related to periprosthetic infection (PJI) in orthopaedic oncology, and to identify areas for future research. METHODS: In January 2024, the Birmingham Orthopaedic Oncology Meeting (BOOM) held in Birmingham, UK, gathered 309 delegates from 53 countries to debate 20 consensus statements on PJI in orthopaedic oncology using a modified Delphi process. RESULTS: Of 20 questions and statements on PJI in orthopaedic oncology, none achieved unanimous consensus, 18 achieved strong consensus, one achieved moderate consensus, and one achieved weak consensus. The statements that reached consensus with notable agreement were on the prophylaxis of infection, management of leaking wounds, and surgical strategies for the treatment of PJI. Short-duration antibiotic prophylaxis was deemed as effective as longer courses for lower-risk reconstructions, and aggressive management was recommended for wounds draining beyond five to seven days to prevent deep infection. Furthermore, single-stage, two-stage, and 1.5-stage revision were recognized as valid strategies, with two-stage revision remaining the most reliable. The statements that did not achieve consensus were on the role of debridement, antibiotics, and implant retention and prolonged antibiotic use post-revision. CONCLUSION: The BOOM meeting achieved consensus for important topics on periprosthetic infection in orthopaedic oncology, but highlighted the low quality of the underlying evidence. This study has provided recommendations for the treatment of leaky wounds, duration of postoperative antibiotic prophylaxis, and choice of revision strategy.

Duke Scholars

Published In

Bone Joint J

DOI

EISSN

2049-4408

Publication Date

December 1, 2025

Volume

107-B

Issue

12

Start / End Page

1352 / 1359

Location

England

Related Subject Headings

  • Reoperation
  • Prosthesis-Related Infections
  • Orthopedics
  • Humans
  • Delphi Technique
  • Debridement
  • Consensus
  • Antibiotic Prophylaxis
  • Anti-Bacterial Agents
 

Citation

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Chicago
ICMJE
MLA
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Jeys, L., Botello, E., Boyle, R. A., Ebeid, W., Houdek, M. T., Kurisunkal, V. J., … Zumarraga, J. P. (2025). A modified Delphi consensus on periprosthetic infection in orthopaedic oncology : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM). Bone Joint J, 107-B(12), 1352–1359. https://doi.org/10.1302/0301-620X.107B12.BJJ-2024-1039.R4
Jeys, Lee, Eduardo Botello, Richard A. Boyle, Walid Ebeid, Matthew T. Houdek, Vineet J. Kurisunkal, Rhidian Morgan-Jones, et al. “A modified Delphi consensus on periprosthetic infection in orthopaedic oncology : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).Bone Joint J 107-B, no. 12 (December 1, 2025): 1352–59. https://doi.org/10.1302/0301-620X.107B12.BJJ-2024-1039.R4.
Jeys L, Botello E, Boyle RA, Ebeid W, Houdek MT, Kurisunkal VJ, et al. A modified Delphi consensus on periprosthetic infection in orthopaedic oncology : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM). Bone Joint J. 2025 Dec 1;107-B(12):1352–9.
Jeys, Lee, et al. “A modified Delphi consensus on periprosthetic infection in orthopaedic oncology : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).Bone Joint J, vol. 107-B, no. 12, Dec. 2025, pp. 1352–59. Pubmed, doi:10.1302/0301-620X.107B12.BJJ-2024-1039.R4.
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Published In

Bone Joint J

DOI

EISSN

2049-4408

Publication Date

December 1, 2025

Volume

107-B

Issue

12

Start / End Page

1352 / 1359

Location

England

Related Subject Headings

  • Reoperation
  • Prosthesis-Related Infections
  • Orthopedics
  • Humans
  • Delphi Technique
  • Debridement
  • Consensus
  • Antibiotic Prophylaxis
  • Anti-Bacterial Agents