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Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report.

Publication ,  Journal Article
Salameh, Y; Lyles, J; Yousef, S
Published in: Respir Med Case Rep
2025

Cystic Fibrosis leads to liver complications, including cystic fibrosis liver disease but hyperbilirubinemia in CF patients on CFTR modulators is less understood. This article describes two pediatric CF patients on Elexacaftor/Tezacaftor/Ivacaftor therapy with elevated bilirubin, ultimately diagnosed with Gilbert syndrome, highlighting the importance of fractionated bilirubin testing for early diagnosis and management.

Duke Scholars

Published In

Respir Med Case Rep

DOI

ISSN

2213-0071

Publication Date

2025

Volume

58

Start / End Page

102340

Location

England

Related Subject Headings

  • 3201 Cardiovascular medicine and haematology
 

Citation

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Salameh, Y., Lyles, J., & Yousef, S. (2025). Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report. Respir Med Case Rep, 58, 102340. https://doi.org/10.1016/j.rmcr.2025.102340
Salameh, Yara, John Lyles, and Shatha Yousef. “Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report.Respir Med Case Rep 58 (2025): 102340. https://doi.org/10.1016/j.rmcr.2025.102340.
Salameh Y, Lyles J, Yousef S. Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report. Respir Med Case Rep. 2025;58:102340.
Salameh, Yara, et al. “Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report.Respir Med Case Rep, vol. 58, 2025, p. 102340. Pubmed, doi:10.1016/j.rmcr.2025.102340.
Salameh Y, Lyles J, Yousef S. Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report. Respir Med Case Rep. 2025;58:102340.
Journal cover image

Published In

Respir Med Case Rep

DOI

ISSN

2213-0071

Publication Date

2025

Volume

58

Start / End Page

102340

Location

England

Related Subject Headings

  • 3201 Cardiovascular medicine and haematology