Skip to main content

Osteoarthritis physical activity care pathway: Results of an exploratory trial.

Publication ,  Journal Article
Allen, KD; Huffman, KF; Callahan, LF; Fullenkamp, N; Golightly, YM; Hales, DP; Nelson, AE; Ntim, S; Pathak, A; Rees, J; Vasa, R; Vu, MB; Cleveland, RJ
Published in: Osteoarthr Cartil Open
March 2026

OBJECTIVE: To conduct an exploratory randomized controlled trial of a physical activity intervention for individuals with osteoarthritis (OA) involving telephone-delivered coaching, activity self-monitoring, and connection with resources to support activity (Osteoarthritis Physical Activity Care Pathway; OA-PCP). METHODS: Older adults (age ≥65 years) with symptomatic hip or knee OA and comorbid health conditions (N ​= ​240) were randomized to OA-PCP or an attention control (AC) condition. OA-PCP included coaching calls at baseline and at 3-month intervals through 12 months, as well as email-delivered content. The ACgroup received calls and emails focused on OA education. The primary outcome was minutes of moderate to vigorous physical activity (MVPA) per week, measured at baseline, 6-months and 12-months via accelerometer. Secondary outcomes included other physical activity metrics and the Western Ontario and McMaster Universities Osteoarthritis Index pain and function subscales. Linear mixed regression was used to estimate between-group differences from baseline to follow-up time points. RESULTS: At 6-month and 12-month follow-up, the changes in weekly MVPA favored the OA-PCP by 9.5 ​min (95 ​% Confidence Interval -6.7, 25.8; p ​= ​0.252) and 12.3 ​min (95 ​% Confidence Interval -3.8, 28.4; p ​= ​0.136), respectively, but differences were not statistically or clinically significant. There were no significant between-group differences in secondary outcomes other than steps per day at 12-months. CONCLUSIONS: A more intensive intervention approach may be needed to enhance physical activity among older adults with OA and comorbid health conditions.

Duke Scholars

Published In

Osteoarthr Cartil Open

DOI

EISSN

2665-9131

Publication Date

March 2026

Volume

8

Issue

1

Start / End Page

100724

Location

England

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Allen, K. D., Huffman, K. F., Callahan, L. F., Fullenkamp, N., Golightly, Y. M., Hales, D. P., … Cleveland, R. J. (2026). Osteoarthritis physical activity care pathway: Results of an exploratory trial. Osteoarthr Cartil Open, 8(1), 100724. https://doi.org/10.1016/j.ocarto.2025.100724
Allen, Kelli D., Katie F. Huffman, Leigh F. Callahan, Natalie Fullenkamp, Yvonne M. Golightly, Derek P. Hales, Amanda E. Nelson, et al. “Osteoarthritis physical activity care pathway: Results of an exploratory trial.Osteoarthr Cartil Open 8, no. 1 (March 2026): 100724. https://doi.org/10.1016/j.ocarto.2025.100724.
Allen KD, Huffman KF, Callahan LF, Fullenkamp N, Golightly YM, Hales DP, et al. Osteoarthritis physical activity care pathway: Results of an exploratory trial. Osteoarthr Cartil Open. 2026 Mar;8(1):100724.
Allen, Kelli D., et al. “Osteoarthritis physical activity care pathway: Results of an exploratory trial.Osteoarthr Cartil Open, vol. 8, no. 1, Mar. 2026, p. 100724. Pubmed, doi:10.1016/j.ocarto.2025.100724.
Allen KD, Huffman KF, Callahan LF, Fullenkamp N, Golightly YM, Hales DP, Nelson AE, Ntim S, Pathak A, Rees J, Vasa R, Vu MB, Cleveland RJ. Osteoarthritis physical activity care pathway: Results of an exploratory trial. Osteoarthr Cartil Open. 2026 Mar;8(1):100724.

Published In

Osteoarthr Cartil Open

DOI

EISSN

2665-9131

Publication Date

March 2026

Volume

8

Issue

1

Start / End Page

100724

Location

England

Related Subject Headings

  • 3202 Clinical sciences