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Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High-Risk Management.

Publication ,  Journal Article
Ringen, K; Dement, JM; Cloeren, M; Almashat, S; Grier, W; Hines, S; Welch, LS; Cranford, K; Haas, S; Quinn, P; Chen, A; Fisher, M
Published in: Am J Ind Med
April 2026

BACKGROUND: Since 1997 the Building Trades National Medical Screening Program (BTMed) has offered medical exams to construction workers employed in US nuclear weapons facilities. The process consists of two steps: (1) a detailed work history interview; and (2) a medical exam. Some participants only completed the work history interview, and we compared their mortality experience to those who also completed medical exams. METHODS: We compared the mortality of 3470 work-history-only participants to 23,452 participants who completed both the work history interview and medical exams and, of these, 1720 who additionally participated in lung cancer screening. We used Cox proportional hazard and Poisson regression models to estimate hazard ratios and risk ratios while controlling for potential confounders. RESULTS: Medical exam participants experienced a reduction in mortality risk of 28% for all causes combined; 27% for all respiratory diseases combined; 37% for chronic obstructive pulmonary disease; 30% for cardiovascular diseases combined; 32% for all cancers combined; 36% for lung cancer; and 53% for colorectal cancer. The more medical exams they undertook the greater the mortality risk reduction (25%, 29%, and 43% for one, two, and three medical exams, respectively), demonstrating a clear trend. BTMed has prevented approximately 2911 premature deaths among our participants through 2021 and added 35,178 years of life, an average of 1.5 years per participant, at a cost of $2757 per year of life saved. CONCLUSIONS: Secondary prevention in occupational high-risk groups is very effective. Continued surveillance beyond retirement age is important to reduce mortality.

Duke Scholars

Published In

Am J Ind Med

DOI

EISSN

1097-0274

Publication Date

April 2026

Volume

69

Issue

4

Start / End Page

241 / 253

Location

United States

Related Subject Headings

  • United States
  • Secondary Prevention
  • Pulmonary Disease, Chronic Obstructive
  • Proportional Hazards Models
  • Occupational Health
  • Occupational Exposure
  • Occupational Diseases
  • Nuclear Weapons
  • Middle Aged
  • Mass Screening
 

Citation

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Ringen, K., Dement, J. M., Cloeren, M., Almashat, S., Grier, W., Hines, S., … Fisher, M. (2026). Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High-Risk Management. Am J Ind Med, 69(4), 241–253. https://doi.org/10.1002/ajim.70052
Ringen, Knut, John M. Dement, Marianne Cloeren, Sammy Almashat, William Grier, Stella Hines, Laura S. Welch, et al. “Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High-Risk Management.Am J Ind Med 69, no. 4 (April 2026): 241–53. https://doi.org/10.1002/ajim.70052.
Ringen K, Dement JM, Cloeren M, Almashat S, Grier W, Hines S, et al. Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High-Risk Management. Am J Ind Med. 2026 Apr;69(4):241–53.
Ringen, Knut, et al. “Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High-Risk Management.Am J Ind Med, vol. 69, no. 4, Apr. 2026, pp. 241–53. Pubmed, doi:10.1002/ajim.70052.
Ringen K, Dement JM, Cloeren M, Almashat S, Grier W, Hines S, Welch LS, Cranford K, Haas S, Quinn P, Chen A, Fisher M. Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High-Risk Management. Am J Ind Med. 2026 Apr;69(4):241–253.
Journal cover image

Published In

Am J Ind Med

DOI

EISSN

1097-0274

Publication Date

April 2026

Volume

69

Issue

4

Start / End Page

241 / 253

Location

United States

Related Subject Headings

  • United States
  • Secondary Prevention
  • Pulmonary Disease, Chronic Obstructive
  • Proportional Hazards Models
  • Occupational Health
  • Occupational Exposure
  • Occupational Diseases
  • Nuclear Weapons
  • Middle Aged
  • Mass Screening