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ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation.

Publication ,  Journal Article
Courtwright, AM; Mackintosh, JA; Alder, JK; Garcia, CK; Froidure, A; Lowery, E; Hayes, D; Pali, S; Philippot, Q; Borie, R; Greenland, JR ...
Published in: J Heart Lung Transplant
February 2026

Motivated by growing evidence that the presence of critically shortened telomeres influences interstitial lung disease (ILD) trajectories and is associated with extrapulmonary conditions relevant to lung transplant candidacy and post-transplant complications, this Consensus Statement aims to address gaps in the evaluation and management of patients with short telomere syndrome (STS). These considerations reflect the work of an international Writing Committee with expertise in STS and are grounded in current literature and expert consensus. The need for this document arises from the recognition that STS is an underdiagnosed contributor to ILD, and that its presence introduces complexities that require dedicated, multidisciplinary attention in the transplant setting.

Duke Scholars

Published In

J Heart Lung Transplant

DOI

EISSN

1557-3117

Publication Date

February 2026

Volume

45

Issue

2

Start / End Page

e83 / e103

Location

United States

Related Subject Headings

  • Telomere Shortening
  • Surgery
  • Societies, Medical
  • Lung Transplantation
  • Lung Diseases, Interstitial
  • Humans
  • Consensus
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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ICMJE
MLA
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Courtwright, A. M., Mackintosh, J. A., Alder, J. K., Garcia, C. K., Froidure, A., Lowery, E., … McDyer, J. (2026). ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation. J Heart Lung Transplant, 45(2), e83–e103. https://doi.org/10.1016/j.healun.2025.10.028
Courtwright, Andrew M., John A. Mackintosh, Jonathan K. Alder, Christine Kim Garcia, Antoine Froidure, Erin Lowery, Don Hayes, et al. “ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation.J Heart Lung Transplant 45, no. 2 (February 2026): e83–103. https://doi.org/10.1016/j.healun.2025.10.028.
Courtwright AM, Mackintosh JA, Alder JK, Garcia CK, Froidure A, Lowery E, et al. ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation. J Heart Lung Transplant. 2026 Feb;45(2):e83–103.
Courtwright, Andrew M., et al. “ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation.J Heart Lung Transplant, vol. 45, no. 2, Feb. 2026, pp. e83–103. Pubmed, doi:10.1016/j.healun.2025.10.028.
Courtwright AM, Mackintosh JA, Alder JK, Garcia CK, Froidure A, Lowery E, Hayes D, Pali S, Philippot Q, Borie R, Greenland JR, Mannem H, Snyder ME, Hellemons M, Snyder LD, McDyer J. ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation. J Heart Lung Transplant. 2026 Feb;45(2):e83–e103.
Journal cover image

Published In

J Heart Lung Transplant

DOI

EISSN

1557-3117

Publication Date

February 2026

Volume

45

Issue

2

Start / End Page

e83 / e103

Location

United States

Related Subject Headings

  • Telomere Shortening
  • Surgery
  • Societies, Medical
  • Lung Transplantation
  • Lung Diseases, Interstitial
  • Humans
  • Consensus
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology