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Postoperative infection rates with 3D-printed custom metallic cage implants comparable to traditional reconstruction in the foot and ankle.

Journal articles  - Journal Article
Parsons, KE; LoPolito, A; Shenoy, DA; Anastasio, AT; O'Neill, CN; Adams, SB
Published in: Foot Ankle Surg
July 2026

BACKGROUND: Treatment of foot and ankle critical-sized defects (CSDs) remains a surgical challenge. Custom 3D-printed metallic implants have emerged as a promising solution, however current literature is limited. This study evaluated the incidence and associated factors of deep postoperative infection following custom cage implantation. METHODS: A retrospective cohort study was conducted on 62 patients who underwent custom cage implant arthrodesis. Pre-, peri-, and postoperative variables were collected, with deep postoperative infection as the primary outcome. RESULTS: Of 62 patients, 13 (21 %) developed deep postoperative infections at a median 957 days. Superficial wound breakdown was significantly associated with infection. History of ipsilateral foot and ankle infection, diabetes, smoking, and neuropathy were not significantly associated with infection. CONCLUSION: Infection rates after custom cage implantation were comparable to those of traditional CSD management methods. These findings support continued evaluation of custom cage implants and emphasize the importance of reducing postoperative infection risk. LEVEL OF EVIDENCE: III.

Duke Scholars

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Published In

Foot Ankle Surg

DOI

EISSN

1460-9584

Publication Date

July 2026

Volume

32

Issue

5

Start / End Page

510 / 520

Location

France

Related Subject Headings

  • Surgical Wound Infection
  • Retrospective Studies
  • Prosthesis Design
  • Prostheses and Implants
  • Printing, Three-Dimensional
  • Orthopedics
  • Middle Aged
  • Male
  • Incidence
  • Humans
 

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Parsons, K. E., LoPolito, A., Shenoy, D. A., Anastasio, A. T., O’Neill, C. N., & Adams, S. B. (2026). Postoperative infection rates with 3D-printed custom metallic cage implants comparable to traditional reconstruction in the foot and ankle. Foot Ankle Surg, 32(5), 510–520. https://doi.org/10.1016/j.fas.2026.01.006
Parsons, Katelyn E., Andrew LoPolito, Devika A. Shenoy, Albert T. Anastasio, Conor N. O’Neill, and Samuel B. Adams. “Postoperative infection rates with 3D-printed custom metallic cage implants comparable to traditional reconstruction in the foot and ankle.Foot Ankle Surg 32, no. 5 (July 2026): 510–20. https://doi.org/10.1016/j.fas.2026.01.006.
Parsons KE, LoPolito A, Shenoy DA, Anastasio AT, O’Neill CN, Adams SB. Postoperative infection rates with 3D-printed custom metallic cage implants comparable to traditional reconstruction in the foot and ankle. Foot Ankle Surg. 2026 Jul;32(5):510–20.
Parsons, Katelyn E., et al. “Postoperative infection rates with 3D-printed custom metallic cage implants comparable to traditional reconstruction in the foot and ankle.Foot Ankle Surg, vol. 32, no. 5, July 2026, pp. 510–20. Pubmed, doi:10.1016/j.fas.2026.01.006.
Parsons KE, LoPolito A, Shenoy DA, Anastasio AT, O’Neill CN, Adams SB. Postoperative infection rates with 3D-printed custom metallic cage implants comparable to traditional reconstruction in the foot and ankle. Foot Ankle Surg. 2026 Jul;32(5):510–520.
Journal cover image

Published In

Foot Ankle Surg

DOI

EISSN

1460-9584

Publication Date

July 2026

Volume

32

Issue

5

Start / End Page

510 / 520

Location

France

Related Subject Headings

  • Surgical Wound Infection
  • Retrospective Studies
  • Prosthesis Design
  • Prostheses and Implants
  • Printing, Three-Dimensional
  • Orthopedics
  • Middle Aged
  • Male
  • Incidence
  • Humans