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A cloud-edge reference architecture for intertwining health digital domains.

Publication ,  Journal Article
Tramontano, A; Tamburis, O; Perillo, G; Iaccarino, G; Benis, A; Magliulo, M
Published in: Health informatics journal
January 2026

Objective: In the present work, LinkAll is introduced as a novel architectural model designed to enable real-time monitoring and cross-referential data analysis in remote monitoring systems across human, animal, and environmental health domains. LinkAll leverages Edge-Computing and Internet of Things principles to handle data collection, processing, and presentation from various sources. Methods: Two sibling systems were implemented to demonstrate its capability, one for monitoring urban greenery and the other for elderly home care. These systems were evaluated based on their ability to integrate with existing information systems, collect biophysical parameters, and ensure data cross-referencing. Results: Both systems demonstrate effective pluggability and cross-referenceability performances, meeting the stakeholders' requirements. LinkAll's ability to integrate diverse sensors and devices into existing infrastructures while providing real-time, machine-actionable insights, is also underscored. Conclusion: Pluggability, cross-referenceability, and compliance with FAIR principles make the architectural model introduced a robust solution for integrating human, animal, and environmental health monitoring systems, enhancing decision-making and contributing to One (Digital) Health's strategic goals.

Duke Scholars

Published In

Health informatics journal

DOI

EISSN

1741-2811

ISSN

1460-4582

Publication Date

January 2026

Volume

32

Issue

1

Start / End Page

14604582251383803

Related Subject Headings

  • Remote Sensing Technology
  • Medical Informatics
  • Environmental Health
  • Digital Health
  • Cloud Computing
  • Animals
  • 4601 Applied computing
  • 4203 Health services and systems
 

Citation

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ICMJE
MLA
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Tramontano, A., Tamburis, O., Perillo, G., Iaccarino, G., Benis, A., & Magliulo, M. (2026). A cloud-edge reference architecture for intertwining health digital domains. Health Informatics Journal, 32(1), 14604582251383804. https://doi.org/10.1177/14604582251383803
Tramontano, Adriano, Oscar Tamburis, Giulio Perillo, Guido Iaccarino, Arriel Benis, and Mario Magliulo. “A cloud-edge reference architecture for intertwining health digital domains.Health Informatics Journal 32, no. 1 (January 2026): 14604582251383804. https://doi.org/10.1177/14604582251383803.
Tramontano A, Tamburis O, Perillo G, Iaccarino G, Benis A, Magliulo M. A cloud-edge reference architecture for intertwining health digital domains. Health informatics journal. 2026 Jan;32(1):14604582251383804.
Tramontano, Adriano, et al. “A cloud-edge reference architecture for intertwining health digital domains.Health Informatics Journal, vol. 32, no. 1, Jan. 2026, p. 14604582251383804. Epmc, doi:10.1177/14604582251383803.
Tramontano A, Tamburis O, Perillo G, Iaccarino G, Benis A, Magliulo M. A cloud-edge reference architecture for intertwining health digital domains. Health informatics journal. 2026 Jan;32(1):14604582251383804.
Journal cover image

Published In

Health informatics journal

DOI

EISSN

1741-2811

ISSN

1460-4582

Publication Date

January 2026

Volume

32

Issue

1

Start / End Page

14604582251383803

Related Subject Headings

  • Remote Sensing Technology
  • Medical Informatics
  • Environmental Health
  • Digital Health
  • Cloud Computing
  • Animals
  • 4601 Applied computing
  • 4203 Health services and systems