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Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial.

Publication ,  Journal Article
Agunbiade, S; Gbaja-Biamila, T; Oladele, D; Obiezu-Umeh, C; Musa, AZ; Blessing, LA; Tahlil, KM; Akinsolu, FT; Conserve, DF; Adeoti, E; Xian, H ...
Published in: Drug and alcohol dependence
June 2025

Adolescents and young adults (AYA, 14-24 years old) have the highest rates of drug use in most low- and middle-income countries. Little is known about the drivers of drug use among AYA in Nigeria and harm reduction services are limited.A secondary data analysis was performed of the baseline survey of the 'I-TEST' study involving AYA in Nigeria. The two primary outcomes of interest were lifetime measures of drug use and needle sharing. Logistic regression analyses were performed to obtain odds ratios for the associations between socio-demographic exposures and the two primary outcomes. Odds ratios were subsequently adjusted for age and sex.1500 AYA survey responses were analysed. Respondents were mostly unemployed, students, and living in southern Nigeria. Drug use was reported by 301/1500(20.3 %) AYA. Among these, 213/301(71.5 %) reported needle sharing. Drug use did not vary by age (OR:0.94, 95 %CI:0.73-1.22) or sex (OR:1.00, 95 %CI:0.77-1.28). AYA in the North-Central zone had higher odds of drug use (OR:1.86, 95 %CI:1.28-2.69) and needle sharing (OR:2.51, 95 %CI:1.07-5.91) compared to AYA in the South-West zone of Nigeria. AYA aged 14-19 had higher odds of needle sharing compared to those aged 20-24 (OR:3.49, 95 %CI:1.94-6.26). Female AYA had higher odds of needle sharing compared to males (OR:5.05, 95 %CI:2.85-8.95).Drug use and needle sharing are common among AYA in Nigeria. There is an urgent need for harm reduction services and research informed by AYA.

Duke Scholars

Published In

Drug and alcohol dependence

DOI

EISSN

1879-0046

ISSN

0376-8716

Publication Date

June 2025

Volume

271

Start / End Page

112666

Related Subject Headings

  • Young Adult
  • Substance-Related Disorders
  • Substance Abuse
  • Nigeria
  • Needle Sharing
  • Male
  • Humans
  • Female
  • Cross-Sectional Studies
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
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Agunbiade, S., Gbaja-Biamila, T., Oladele, D., Obiezu-Umeh, C., Musa, A. Z., Blessing, L. A., … Tucker, J. (2025). Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial. Drug and Alcohol Dependence, 271, 112666. https://doi.org/10.1016/j.drugalcdep.2025.112666
Agunbiade, Simisola, Titilola Gbaja-Biamila, David Oladele, Chisom Obiezu-Umeh, Adesola Zaidat Musa, Lateef Akeem Blessing, Kadija Muse Tahlil, et al. “Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial.Drug and Alcohol Dependence 271 (June 2025): 112666. https://doi.org/10.1016/j.drugalcdep.2025.112666.
Agunbiade S, Gbaja-Biamila T, Oladele D, Obiezu-Umeh C, Musa AZ, Blessing LA, et al. Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial. Drug and alcohol dependence. 2025 Jun;271:112666.
Agunbiade, Simisola, et al. “Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial.Drug and Alcohol Dependence, vol. 271, June 2025, p. 112666. Epmc, doi:10.1016/j.drugalcdep.2025.112666.
Agunbiade S, Gbaja-Biamila T, Oladele D, Obiezu-Umeh C, Musa AZ, Blessing LA, Tahlil KM, Akinsolu FT, Conserve DF, Adeoti E, Xian H, Kuriakose K, Iwelunmor J, Ezechi O, Tucker J. Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial. Drug and alcohol dependence. 2025 Jun;271:112666.
Journal cover image

Published In

Drug and alcohol dependence

DOI

EISSN

1879-0046

ISSN

0376-8716

Publication Date

June 2025

Volume

271

Start / End Page

112666

Related Subject Headings

  • Young Adult
  • Substance-Related Disorders
  • Substance Abuse
  • Nigeria
  • Needle Sharing
  • Male
  • Humans
  • Female
  • Cross-Sectional Studies
  • Adult