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Innovating global regulatory frameworks for generative AI in medical devices is an urgent priority.

Publication ,  Journal Article
Ong, JCL; Ning, Y; Liu, M; Ma, Y; Zhao, L; Singh, K; Chang, RT; Vogel, S; Lim, JCW; Tan, ISK; Freyer, O; Gilbert, S; Bitterman, DS; Liu, X ...
Published in: NPJ Digit Med
March 19, 2026

The integration of generative AI (GenAI) and large language models (LLMs) in healthcare presents both unprecedented opportunities and challenges, necessitating innovative regulatory approaches. In this perspective, we discuss the risks of GenAI and LLM-based medical devices, the limitations of current medical device regulation frameworks when applied to GenAI or LLMs, and advocate for global collaboration in regulatory science research through engaging multidisciplinary expertise and focusing on the needs of diverse populations.

Duke Scholars

Published In

NPJ Digit Med

DOI

EISSN

2398-6352

Publication Date

March 19, 2026

Location

England

Related Subject Headings

  • 4203 Health services and systems
 

Citation

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Ong, J. C. L., Ning, Y., Liu, M., Ma, Y., Zhao, L., Singh, K., … Liu, N. (2026). Innovating global regulatory frameworks for generative AI in medical devices is an urgent priority. NPJ Digit Med. https://doi.org/10.1038/s41746-026-02552-2
Ong, Jasmine Chiat Ling, Yilin Ning, Mingxuan Liu, Yian Ma, Liang Zhao, Kuldev Singh, Robert T. Chang, et al. “Innovating global regulatory frameworks for generative AI in medical devices is an urgent priority.NPJ Digit Med, March 19, 2026. https://doi.org/10.1038/s41746-026-02552-2.
Ong JCL, Ning Y, Liu M, Ma Y, Zhao L, Singh K, et al. Innovating global regulatory frameworks for generative AI in medical devices is an urgent priority. NPJ Digit Med. 2026 Mar 19;
Ong, Jasmine Chiat Ling, et al. “Innovating global regulatory frameworks for generative AI in medical devices is an urgent priority.NPJ Digit Med, Mar. 2026. Pubmed, doi:10.1038/s41746-026-02552-2.
Ong JCL, Ning Y, Liu M, Ma Y, Zhao L, Singh K, Chang RT, Vogel S, Lim JCW, Tan ISK, Freyer O, Gilbert S, Bitterman DS, Liu X, Denniston AK, Liu N. Innovating global regulatory frameworks for generative AI in medical devices is an urgent priority. NPJ Digit Med. 2026 Mar 19;

Published In

NPJ Digit Med

DOI

EISSN

2398-6352

Publication Date

March 19, 2026

Location

England

Related Subject Headings

  • 4203 Health services and systems