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Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults.

Publication ,  Journal Article
Filigrana, P; Moon, J-Y; Gallo, LC; González, HM; Lipton, RB; Tarraf, W; Kaplan, RC; Daviglus, ML; Testai, FD; Marquine, MJ; Cai, J; Isasi, CR ...
Published in: Neurology
April 14, 2026

BACKGROUND AND OBJECTIVES: Low life-course socioeconomic position (SEP) has been associated with worse cognitive function in older age. However, its association with brain structure remains unclear. We assessed whether SEP at 3 periods of the life-course and socioeconomic mobility are associated with later-life MRI-derived brain volumes. METHODS: We used longitudinal data from the Hispanic Community Health Study/Study of Latinos and its Investigations of Neurocognitive Aging-MRI ancillary study. We determined childhood SEP using participant self-reports of their parent's educational attainment (

Duke Scholars

Published In

Neurology

DOI

EISSN

1526-632X

Publication Date

April 14, 2026

Volume

106

Issue

7

Start / End Page

e214716

Location

United States

Related Subject Headings

  • White
  • United States
  • Social Class
  • Organ Size
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Longitudinal Studies
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
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Filigrana, P., Moon, J.-Y., Gallo, L. C., González, H. M., Lipton, R. B., Tarraf, W., … Isasi, C. R. (2026). Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults. Neurology, 106(7), e214716. https://doi.org/10.1212/WNL.0000000000214716
Filigrana, Paola, Jee-Young Moon, Linda C. Gallo, Hector M. González, Richard B. Lipton, Wassim Tarraf, Robert C. Kaplan, et al. “Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults.Neurology 106, no. 7 (April 14, 2026): e214716. https://doi.org/10.1212/WNL.0000000000214716.
Filigrana P, Moon J-Y, Gallo LC, González HM, Lipton RB, Tarraf W, et al. Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults. Neurology. 2026 Apr 14;106(7):e214716.
Filigrana, Paola, et al. “Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults.Neurology, vol. 106, no. 7, Apr. 2026, p. e214716. Pubmed, doi:10.1212/WNL.0000000000214716.
Filigrana P, Moon J-Y, Gallo LC, González HM, Lipton RB, Tarraf W, Kaplan RC, Daviglus ML, Testai FD, Marquine MJ, Cai J, Perreira KM, Stickel AM, DeCarli C, Isasi CR. Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults. Neurology. 2026 Apr 14;106(7):e214716.

Published In

Neurology

DOI

EISSN

1526-632X

Publication Date

April 14, 2026

Volume

106

Issue

7

Start / End Page

e214716

Location

United States

Related Subject Headings

  • White
  • United States
  • Social Class
  • Organ Size
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Longitudinal Studies
  • Humans