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A Randomized Trial Testing a Body-Focused Exposure Treatment for Functional Abdominal Pain in Children.

Publication ,  Journal Article
Zucker, NL; Pendergast, J; Rivera-Cancel, A; Ives, L; Small, B; Gagliano, ME; Lewis, G; Davila, M; Walter, BK; Datta, N; Erwin, S; Farber, M ...
Published in: Am J Gastroenterol
March 31, 2026

BACKGROUND: Functional abdominal pain (FAP) in young children is common, persistent, and associated with significant impairment and risk for later anxiety disorders. Current treatments often emphasize distraction from pain, which may preclude long-term fear reduction. We tested a novel exposure-based intervention that encourages children to focus on potentially uncomfortable bodily sensations with playful curiosity (Feeling and Body Investigators; FBI) compared to developmentally modified components of current best practices emphasizing distraction (Caregivers in Action; CIA). METHOD: In a randomized clinical trial, 107 parent-child dyads (children ages 5-9 with FAP) were assigned to either the FBI or CIA condition, each consisting of ten weekly sessions. Primary outcomes were child- and parent-reported pain intensity, frequency, duration, and interference. Secondary outcomes were negative affect and pain-related distress. Mixed-model and non-parametric analyses evaluated within- and between-group changes. RESULTS: Both interventions resulted in significant reductions in pain intensity, frequency, duration, and interference, as well as improvements in negative affect and distress (all p < .01). However, neither approach was shown to be superior. Both treatments were rated highly acceptable by parents and children, with over 90% of parents reporting the treatment helped them manage their child's symptoms. CONCLUSION: Both the FBI and CIA interventions reduced pain and improved emotional functioning in young children with FAP. Although the two approaches differed in their focus on attention to pain and use of exposure strategies, they were not significantly different. These findings provide pediatricians and mental health providers with evidence-based options for treating young children with FAP.

Duke Scholars

Published In

Am J Gastroenterol

DOI

EISSN

1572-0241

Publication Date

March 31, 2026

Location

United States

Related Subject Headings

  • Gastroenterology & Hepatology
  • 3202 Clinical sciences
 

Citation

APA
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ICMJE
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Zucker, N. L., Pendergast, J., Rivera-Cancel, A., Ives, L., Small, B., Gagliano, M. E., … Egger, H. (2026). A Randomized Trial Testing a Body-Focused Exposure Treatment for Functional Abdominal Pain in Children. Am J Gastroenterol. https://doi.org/10.14309/ajg.0000000000004010
Zucker, Nancy L., Jane Pendergast, Alannah Rivera-Cancel, Lindsay Ives, Brian Small, Martha E. Gagliano, Gregory Lewis, et al. “A Randomized Trial Testing a Body-Focused Exposure Treatment for Functional Abdominal Pain in Children.Am J Gastroenterol, March 31, 2026. https://doi.org/10.14309/ajg.0000000000004010.
Zucker NL, Pendergast J, Rivera-Cancel A, Ives L, Small B, Gagliano ME, et al. A Randomized Trial Testing a Body-Focused Exposure Treatment for Functional Abdominal Pain in Children. Am J Gastroenterol. 2026 Mar 31;
Zucker, Nancy L., et al. “A Randomized Trial Testing a Body-Focused Exposure Treatment for Functional Abdominal Pain in Children.Am J Gastroenterol, Mar. 2026. Pubmed, doi:10.14309/ajg.0000000000004010.
Zucker NL, Pendergast J, Rivera-Cancel A, Ives L, Small B, Gagliano ME, Lewis G, Davila M, Walter BK, Datta N, Erwin S, Farber M, Romer AL, Gil C, Pilato I, Stein K, Craske M, van Tilburg MAL, Maslow G, Egger H. A Randomized Trial Testing a Body-Focused Exposure Treatment for Functional Abdominal Pain in Children. Am J Gastroenterol. 2026 Mar 31;

Published In

Am J Gastroenterol

DOI

EISSN

1572-0241

Publication Date

March 31, 2026

Location

United States

Related Subject Headings

  • Gastroenterology & Hepatology
  • 3202 Clinical sciences