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Bone marrow transplantation. Part II--autologous.

Publication ,  Journal Article
Chao, NJ; Blume, KG
Published in: West J Med
January 1990

Autologous bone marrow transplantation provides an effective form of "rescue" following high-dose therapy used for treating certain malignant diseases. The high doses of radiotherapy or chemotherapy, or both, should allow for greater tumor cell kill if dose-response to therapy exists for that tumor. The use of autologous bone marrow obviates the need for an HLA-identical donor, and the need for pretransplant immunosuppression; no graft-versus-host disease would ensue. We review in part II the history and background, methods of obtaining autologous stem cells, and details of the results achievable with this type of therapy. We discuss potential difficulties with autologous transplantation, as well as possible future areas of research.

Duke Scholars

Published In

West J Med

ISSN

0093-0415

Publication Date

January 1990

Volume

152

Issue

1

Start / End Page

46 / 51

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Neoplasms
  • Lymphoma
  • Leukemia
  • Humans
  • Hodgkin Disease
  • Forecasting
  • Bone Marrow Transplantation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chao, N. J., & Blume, K. G. (1990). Bone marrow transplantation. Part II--autologous. West J Med, 152(1), 46–51.
Chao, N. J., and K. G. Blume. “Bone marrow transplantation. Part II--autologous.West J Med 152, no. 1 (January 1990): 46–51.
Chao NJ, Blume KG. Bone marrow transplantation. Part II--autologous. West J Med. 1990 Jan;152(1):46–51.
Chao, N. J., and K. G. Blume. “Bone marrow transplantation. Part II--autologous.West J Med, vol. 152, no. 1, Jan. 1990, pp. 46–51.
Chao NJ, Blume KG. Bone marrow transplantation. Part II--autologous. West J Med. 1990 Jan;152(1):46–51.

Published In

West J Med

ISSN

0093-0415

Publication Date

January 1990

Volume

152

Issue

1

Start / End Page

46 / 51

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Neoplasms
  • Lymphoma
  • Leukemia
  • Humans
  • Hodgkin Disease
  • Forecasting
  • Bone Marrow Transplantation