Skip to main content

Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan.

Publication ,  Journal Article
de Oliveira, JS; Auerbach, SB; Sullivan, KM; Sale, GE
Published in: Bone Marrow Transplant
February 1993

A 16-year-old white male with acute biphenotypic leukemia developed evidence of the eosinophilia myalgia syndrome associated with total parenteral nutritional support with solutions containing tryptophan, which were given during his initial induction chemotherapy and also after autologous marrow transplantation. He developed pronounced eosinophilia and a vasculitic skin rash, myalgias of the abdomen, upper trunk, and neck, and died of respiratory distress with no evidence of an infectious etiology. Autopsy revealed diffuse vasculitis involving the heart, lungs, kidneys, testes, spleen, liver, skin, gut wall and marrow with neuritis of gut wall nerves and ganglia. Thus, the eosinophilia myalgia syndrome can be associated with parenteral tryptophan administration.

Duke Scholars

Published In

Bone Marrow Transplant

ISSN

0268-3369

Publication Date

February 1993

Volume

11

Issue

2

Start / End Page

163 / 167

Location

England

Related Subject Headings

  • Tryptophan
  • Solutions
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Parenteral Nutrition, Total
  • Male
  • Immunology
  • Humans
  • Eosinophilia-Myalgia Syndrome
  • Combined Modality Therapy
  • Bone Marrow Transplantation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
de Oliveira, J. S., Auerbach, S. B., Sullivan, K. M., & Sale, G. E. (1993). Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan. Bone Marrow Transplant, 11(2), 163–167.
Oliveira, J. S. de, S. B. Auerbach, K. M. Sullivan, and G. E. Sale. “Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan.Bone Marrow Transplant 11, no. 2 (February 1993): 163–67.
de Oliveira JS, Auerbach SB, Sullivan KM, Sale GE. Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan. Bone Marrow Transplant. 1993 Feb;11(2):163–7.
de Oliveira, J. S., et al. “Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan.Bone Marrow Transplant, vol. 11, no. 2, Feb. 1993, pp. 163–67.
de Oliveira JS, Auerbach SB, Sullivan KM, Sale GE. Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan. Bone Marrow Transplant. 1993 Feb;11(2):163–167.

Published In

Bone Marrow Transplant

ISSN

0268-3369

Publication Date

February 1993

Volume

11

Issue

2

Start / End Page

163 / 167

Location

England

Related Subject Headings

  • Tryptophan
  • Solutions
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Parenteral Nutrition, Total
  • Male
  • Immunology
  • Humans
  • Eosinophilia-Myalgia Syndrome
  • Combined Modality Therapy
  • Bone Marrow Transplantation