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Age and sex effects on brain morphology.

Publication ,  Journal Article
Passe, TJ; Rajagopalan, P; Tupler, LA; Byrum, CE; MacFall, JR; Krishnan, KR
Published in: Prog Neuropsychopharmacol Biol Psychiatry
November 1997

1. Brain morphology can be assessed readily in vivo using magnetic resonance imaging (MRI). 2. In this study, the effects of age and sex on whole-brain morphology were examined using an operator-controlled computer-segmentation protocol. 3. Results indicated that age was associated with gray-matter volume reduction. 4. Brain-size differences between males and females were primarily attributable to white-matter volume. 5. This study confirms the importance of controlling for age and sex in brain-morphology studies.

Duke Scholars

Published In

Prog Neuropsychopharmacol Biol Psychiatry

DOI

ISSN

0278-5846

Publication Date

November 1997

Volume

21

Issue

8

Start / End Page

1231 / 1237

Location

England

Related Subject Headings

  • Sex Characteristics
  • Reference Values
  • Psychiatry
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Female
  • Brain
 

Citation

APA
Chicago
ICMJE
MLA
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Passe, T. J., Rajagopalan, P., Tupler, L. A., Byrum, C. E., MacFall, J. R., & Krishnan, K. R. (1997). Age and sex effects on brain morphology. Prog Neuropsychopharmacol Biol Psychiatry, 21(8), 1231–1237. https://doi.org/10.1016/s0278-5846(97)00160-7
Passe, T. J., P. Rajagopalan, L. A. Tupler, C. E. Byrum, J. R. MacFall, and K. R. Krishnan. “Age and sex effects on brain morphology.Prog Neuropsychopharmacol Biol Psychiatry 21, no. 8 (November 1997): 1231–37. https://doi.org/10.1016/s0278-5846(97)00160-7.
Passe TJ, Rajagopalan P, Tupler LA, Byrum CE, MacFall JR, Krishnan KR. Age and sex effects on brain morphology. Prog Neuropsychopharmacol Biol Psychiatry. 1997 Nov;21(8):1231–7.
Passe, T. J., et al. “Age and sex effects on brain morphology.Prog Neuropsychopharmacol Biol Psychiatry, vol. 21, no. 8, Nov. 1997, pp. 1231–37. Pubmed, doi:10.1016/s0278-5846(97)00160-7.
Passe TJ, Rajagopalan P, Tupler LA, Byrum CE, MacFall JR, Krishnan KR. Age and sex effects on brain morphology. Prog Neuropsychopharmacol Biol Psychiatry. 1997 Nov;21(8):1231–1237.
Journal cover image

Published In

Prog Neuropsychopharmacol Biol Psychiatry

DOI

ISSN

0278-5846

Publication Date

November 1997

Volume

21

Issue

8

Start / End Page

1231 / 1237

Location

England

Related Subject Headings

  • Sex Characteristics
  • Reference Values
  • Psychiatry
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Female
  • Brain