Skip to main content
Journal cover image

The role of motor activity in diet-induced obesity in C57BL/6J mice.

Publication ,  Journal Article
Brownlow, BS; Petro, A; Feinglos, MN; Surwit, RS
Published in: Physiol Behav
July 1996

Previous research in our laboratory has demonstrated that the C57BL/6J (B/6J) mouse has a predisposition to develop severe obesity if placed on a high-fat diet. In the present study we assessed the role of physical activity in this phenomenon. Obesity-prone B/6J and obesity-resistant A/J mice were placed on one of four diets; high fat/high sucrose, high fat/low sucrose, low fat/high sucrose, and low fat/low sucrose. After 4 months, all animals on the high-fat diets had gained more weight than animals on the low-fat diets, and this phenomenon was greatly exaggerated in B/6J mice. Despite the fact that B/6J mice gained more weight than A/J mice on high-fat diets without consuming more calories, spontaneous motor activity was elevated in B/6J mice compared to A/J mice. There was no effect of the diets on activity either within or across strains. These data suggest that predisposition to diet-induced obesity is not explainable by reduced levels of physical activity.

Duke Scholars

Published In

Physiol Behav

DOI

ISSN

0031-9384

Publication Date

July 1996

Volume

60

Issue

1

Start / End Page

37 / 41

Location

United States

Related Subject Headings

  • Weight Gain
  • Species Specificity
  • Obesity
  • Motor Activity
  • Mice, Obese
  • Mice, Inbred C57BL
  • Mice, Inbred A
  • Mice
  • Male
  • Insulin
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Brownlow, B. S., Petro, A., Feinglos, M. N., & Surwit, R. S. (1996). The role of motor activity in diet-induced obesity in C57BL/6J mice. Physiol Behav, 60(1), 37–41. https://doi.org/10.1016/0031-9384(95)02210-4
Brownlow, B. S., A. Petro, M. N. Feinglos, and R. S. Surwit. “The role of motor activity in diet-induced obesity in C57BL/6J mice.Physiol Behav 60, no. 1 (July 1996): 37–41. https://doi.org/10.1016/0031-9384(95)02210-4.
Brownlow BS, Petro A, Feinglos MN, Surwit RS. The role of motor activity in diet-induced obesity in C57BL/6J mice. Physiol Behav. 1996 Jul;60(1):37–41.
Brownlow, B. S., et al. “The role of motor activity in diet-induced obesity in C57BL/6J mice.Physiol Behav, vol. 60, no. 1, July 1996, pp. 37–41. Pubmed, doi:10.1016/0031-9384(95)02210-4.
Brownlow BS, Petro A, Feinglos MN, Surwit RS. The role of motor activity in diet-induced obesity in C57BL/6J mice. Physiol Behav. 1996 Jul;60(1):37–41.
Journal cover image

Published In

Physiol Behav

DOI

ISSN

0031-9384

Publication Date

July 1996

Volume

60

Issue

1

Start / End Page

37 / 41

Location

United States

Related Subject Headings

  • Weight Gain
  • Species Specificity
  • Obesity
  • Motor Activity
  • Mice, Obese
  • Mice, Inbred C57BL
  • Mice, Inbred A
  • Mice
  • Male
  • Insulin