Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism.
Publication
, Journal Article
Williams, RS; Guthrow, CE; Lefkowitz, RJ
Published in: J Clin Endocrinol Metab
March 1979
Lymphocytes from 12 patients with untreated hyperthyroidism were compared to lymphocytes from age- and sex-matched euthyroid control subjects to test the hypothesis that alterations in beta-adrenergic response mechanisms occur in human hyperthyroidism. The binding of (-)[3H]dihydroalprenolol, a compound previously shown in these cells to label binding sites having the characteristics of beta-adrenergic receptors, was assayed and no significant difference was found between the two groups. In addition, the accumulation of cAMP in response to isoproterenol was determined by RIA and, again, no difference was found.
Duke Scholars
Published In
J Clin Endocrinol Metab
DOI
ISSN
0021-972X
Publication Date
March 1979
Volume
48
Issue
3
Start / End Page
503 / 505
Location
United States
Related Subject Headings
- Thyroxine
- Theophylline
- Receptors, Adrenergic, beta
- Receptors, Adrenergic
- Male
- Lymphocytes
- Isoproterenol
- Hyperthyroidism
- Humans
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Williams, R. S., Guthrow, C. E., & Lefkowitz, R. J. (1979). Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism. J Clin Endocrinol Metab, 48(3), 503–505. https://doi.org/10.1210/jcem-48-3-503
Williams, R. S., C. E. Guthrow, and R. J. Lefkowitz. “Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism.” J Clin Endocrinol Metab 48, no. 3 (March 1979): 503–5. https://doi.org/10.1210/jcem-48-3-503.
Williams RS, Guthrow CE, Lefkowitz RJ. Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism. J Clin Endocrinol Metab. 1979 Mar;48(3):503–5.
Williams, R. S., et al. “Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism.” J Clin Endocrinol Metab, vol. 48, no. 3, Mar. 1979, pp. 503–05. Pubmed, doi:10.1210/jcem-48-3-503.
Williams RS, Guthrow CE, Lefkowitz RJ. Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism. J Clin Endocrinol Metab. 1979 Mar;48(3):503–505.
Published In
J Clin Endocrinol Metab
DOI
ISSN
0021-972X
Publication Date
March 1979
Volume
48
Issue
3
Start / End Page
503 / 505
Location
United States
Related Subject Headings
- Thyroxine
- Theophylline
- Receptors, Adrenergic, beta
- Receptors, Adrenergic
- Male
- Lymphocytes
- Isoproterenol
- Hyperthyroidism
- Humans
- Female