The construction of metal centers in proteins by rational design.
Publication
, Journal Article
Hellinga, HW
Published in: Fold Des
1998
Metalloprotein properties result from the interplay between coordination requirements of the metal center, protein stability, and modulation of the metal center by the surrounding protein matrix. Simple metal centers, which exercise control over the protein by affecting stability or enzyme activity, have been created by rational design. Complex centers, which require control by the protein matrix, have also been constructed.
Duke Scholars
Published In
Fold Des
DOI
ISSN
1359-0278
Publication Date
1998
Volume
3
Issue
1
Start / End Page
R1 / R8
Location
England
Related Subject Headings
- Proteins
- Metals
- Iron-Sulfur Proteins
- Histidine
- Heme
- Enzymes
- Calcium
- Biophysics
Citation
APA
Chicago
ICMJE
MLA
NLM
Hellinga, H. W. (1998). The construction of metal centers in proteins by rational design. Fold Des, 3(1), R1–R8. https://doi.org/10.1016/S1359-0278(98)00001-7
Hellinga, H. W. “The construction of metal centers in proteins by rational design.” Fold Des 3, no. 1 (1998): R1–8. https://doi.org/10.1016/S1359-0278(98)00001-7.
Hellinga HW. The construction of metal centers in proteins by rational design. Fold Des. 1998;3(1):R1–8.
Hellinga, H. W. “The construction of metal centers in proteins by rational design.” Fold Des, vol. 3, no. 1, 1998, pp. R1–8. Pubmed, doi:10.1016/S1359-0278(98)00001-7.
Hellinga HW. The construction of metal centers in proteins by rational design. Fold Des. 1998;3(1):R1–R8.
Published In
Fold Des
DOI
ISSN
1359-0278
Publication Date
1998
Volume
3
Issue
1
Start / End Page
R1 / R8
Location
England
Related Subject Headings
- Proteins
- Metals
- Iron-Sulfur Proteins
- Histidine
- Heme
- Enzymes
- Calcium
- Biophysics