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Electromyography as a recording system for eyeblink conditioning with functional magnetic resonance imaging.

Publication ,  Journal Article
Knuttinen, M-G; Parrish, TB; Weiss, C; LaBar, KS; Gitelman, DR; Power, JM; Mesulam, M-M; Disterhoft, JF
Published in: NeuroImage
October 2002

This study was designed to develop a suitable method of recording eyeblink responses while conducting functional magnetic resonance imaging (fMRI). Given the complexity of this behavioral setup outside of the magnet, this study sought to adapt and further optimize an approach to eyeblink conditioning that would be suitable for conducting event-related fMRI experiments. This method involved the acquisition of electromyographic (EMG) signals from the orbicularis oculi of the right eye, which were subsequently amplified and converted into an optical signal outside of the head coil. This optical signal was converted back into an electrical signal once outside the magnet room. Electromyography (EMG)-detected eyeblinks were used to measure responses in a delay eyeblink conditioning paradigm. Our results indicate that: (1) electromyography is a sensitive method for the detection of eyeblinks during fMRI; (2) minimal interactions or artifacts of the EMG signal were created from the magnetic resonance pulse sequence; and (3) no electromyography-related artifacts were detected in the magnetic resonance images. Furthermore, an analysis of the functional data showed areas of activation that have previously been shown in positron emission tomography studies of human eyeblink conditioning. Our results support the strength of this behavioral setup as a suitable method to be used in association with fMRI.

Duke Scholars

Published In

NeuroImage

DOI

EISSN

1095-9572

ISSN

1053-8119

Publication Date

October 2002

Volume

17

Issue

2

Start / End Page

977 / 987

Related Subject Headings

  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Image Interpretation, Computer-Assisted
  • Humans
  • Female
  • Electromyography
  • Electrocardiography
  • Conditioning, Classical
  • Cerebrovascular Circulation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Knuttinen, M.-G., Parrish, T. B., Weiss, C., LaBar, K. S., Gitelman, D. R., Power, J. M., … Disterhoft, J. F. (2002). Electromyography as a recording system for eyeblink conditioning with functional magnetic resonance imaging. NeuroImage, 17(2), 977–987. https://doi.org/10.1006/nimg.2002.1199
Knuttinen, M. -. G., T. B. Parrish, C. Weiss, K. S. LaBar, D. R. Gitelman, J. M. Power, M. -. M. Mesulam, and J. F. Disterhoft. “Electromyography as a recording system for eyeblink conditioning with functional magnetic resonance imaging.NeuroImage 17, no. 2 (October 2002): 977–87. https://doi.org/10.1006/nimg.2002.1199.
Knuttinen M-G, Parrish TB, Weiss C, LaBar KS, Gitelman DR, Power JM, et al. Electromyography as a recording system for eyeblink conditioning with functional magnetic resonance imaging. NeuroImage. 2002 Oct;17(2):977–87.
Knuttinen, M. .. G., et al. “Electromyography as a recording system for eyeblink conditioning with functional magnetic resonance imaging.NeuroImage, vol. 17, no. 2, Oct. 2002, pp. 977–87. Epmc, doi:10.1006/nimg.2002.1199.
Knuttinen M-G, Parrish TB, Weiss C, LaBar KS, Gitelman DR, Power JM, Mesulam M-M, Disterhoft JF. Electromyography as a recording system for eyeblink conditioning with functional magnetic resonance imaging. NeuroImage. 2002 Oct;17(2):977–987.
Journal cover image

Published In

NeuroImage

DOI

EISSN

1095-9572

ISSN

1053-8119

Publication Date

October 2002

Volume

17

Issue

2

Start / End Page

977 / 987

Related Subject Headings

  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Image Interpretation, Computer-Assisted
  • Humans
  • Female
  • Electromyography
  • Electrocardiography
  • Conditioning, Classical
  • Cerebrovascular Circulation