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MR microscopy of the rat carotid artery after balloon injury by using an implanted imaging coil.

Publication ,  Journal Article
Summers, RM; Hedlund, LW; Cofer, GP; Gottsman, MB; Manibo, JF; Johnson, GA
Published in: Magn Reson Med
June 1995

Neointimal hyperplasia after angioplasty was followed in vivo in rats by using MR microscopy and surgically implanted RF imaging coils. By using an inductively coupled pick-up coil, the arteries were imaged 4 days before and 3, 7, and 14 days after angioplasty with a 3DFT spin echo sequence. Eight of 10 angioplastied rats showed moderate to severe stensois based MR measures of lumen diameter reduction from baseline images. There was a good correlation between total wall thickness between MR and hematoxylin and eosin (H&E)-stained sections obtained on the last day. Arteries in the intact and sham groups remained unchanged from baseline measurements. Because this imaging technique examines the artery under in vivo conditions of arterial pressure and flow, it promises to be a useful tool for evaluating pharmacological and mechanical methods of reducing the incidence of vascular stenosis.

Duke Scholars

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

June 1995

Volume

33

Issue

6

Start / End Page

785 / 789

Location

United States

Related Subject Headings

  • Tunica Intima
  • Rats, Sprague-Dawley
  • Rats
  • Nuclear Medicine & Medical Imaging
  • Microscopy
  • Magnetic Resonance Imaging
  • Hyperplasia
  • Female
  • Carotid Stenosis
  • Carotid Artery, External
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Summers, R. M., Hedlund, L. W., Cofer, G. P., Gottsman, M. B., Manibo, J. F., & Johnson, G. A. (1995). MR microscopy of the rat carotid artery after balloon injury by using an implanted imaging coil. Magn Reson Med, 33(6), 785–789. https://doi.org/10.1002/mrm.1910330607
Summers, R. M., L. W. Hedlund, G. P. Cofer, M. B. Gottsman, J. F. Manibo, and G. A. Johnson. “MR microscopy of the rat carotid artery after balloon injury by using an implanted imaging coil.Magn Reson Med 33, no. 6 (June 1995): 785–89. https://doi.org/10.1002/mrm.1910330607.
Summers RM, Hedlund LW, Cofer GP, Gottsman MB, Manibo JF, Johnson GA. MR microscopy of the rat carotid artery after balloon injury by using an implanted imaging coil. Magn Reson Med. 1995 Jun;33(6):785–9.
Summers, R. M., et al. “MR microscopy of the rat carotid artery after balloon injury by using an implanted imaging coil.Magn Reson Med, vol. 33, no. 6, June 1995, pp. 785–89. Pubmed, doi:10.1002/mrm.1910330607.
Summers RM, Hedlund LW, Cofer GP, Gottsman MB, Manibo JF, Johnson GA. MR microscopy of the rat carotid artery after balloon injury by using an implanted imaging coil. Magn Reson Med. 1995 Jun;33(6):785–789.
Journal cover image

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

June 1995

Volume

33

Issue

6

Start / End Page

785 / 789

Location

United States

Related Subject Headings

  • Tunica Intima
  • Rats, Sprague-Dawley
  • Rats
  • Nuclear Medicine & Medical Imaging
  • Microscopy
  • Magnetic Resonance Imaging
  • Hyperplasia
  • Female
  • Carotid Stenosis
  • Carotid Artery, External