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Recovery of pyruvic acid from biotransformation solutions.

Publication ,  Journal Article
Ma, CQ; Li, JC; Qiu, JH; Wang, M; Xu, P
Published in: Applied microbiology and biotechnology
April 2006

The aim of this investigation was to separate pyruvic acid of biotransformation solutions from lactic acid through complex extraction. For this purpose, complex extraction was investigated from model solutions. Tri-n-octanylamine (TOA) was used as the extractant. The effects of various diluents, the stoichiometry of pyruvic acid to TOA, and the initial pH of the aqueous phase on the extraction process were investigated in this study. The effects of sodium hydroxide (NaOH) and trimethylamine (TMA) on the back extraction process were also studied, respectively. The optimal conditions attained from the model solutions proved efficient on the biotransformation solutions of different concentrations. A total recovery of 71-82% of pyruvic acid was obtained, whereas 89-92% of lactic acid was removed. The purity of pyruvic acid reached 97% after the removal of TMA by a simple distillation.

Duke Scholars

John Chichang Li
Author John Chichang Li Surgery

Published In

Applied microbiology and biotechnology

ISSN

0175-7598

Publication Date

April 2006

Volume

70

Issue

3

Start / End Page

308 / 314

Location

germany

Related Subject Headings

  • Biotechnology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ma, C. Q., Li, J. C., Qiu, J. H., Wang, M., & Xu, P. (2006). Recovery of pyruvic acid from biotransformation solutions. Applied Microbiology and Biotechnology, 70(3), 308–314.
Ma, C. Q., J. C. Li, J. H. Qiu, M. Wang, and P. Xu. “Recovery of pyruvic acid from biotransformation solutions.” Applied Microbiology and Biotechnology 70, no. 3 (April 2006): 308–14.
Ma CQ, Li JC, Qiu JH, Wang M, Xu P. Recovery of pyruvic acid from biotransformation solutions. Applied microbiology and biotechnology. 2006 Apr;70(3):308–14.
Ma, C. Q., et al. “Recovery of pyruvic acid from biotransformation solutions.” Applied Microbiology and Biotechnology, vol. 70, no. 3, Apr. 2006, pp. 308–14.
Ma CQ, Li JC, Qiu JH, Wang M, Xu P. Recovery of pyruvic acid from biotransformation solutions. Applied microbiology and biotechnology. 2006 Apr;70(3):308–314.
Journal cover image

Published In

Applied microbiology and biotechnology

ISSN

0175-7598

Publication Date

April 2006

Volume

70

Issue

3

Start / End Page

308 / 314

Location

germany

Related Subject Headings

  • Biotechnology