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Hepatoprotective activity of the constituents in Swertia pseudochinensis.

Publication ,  Journal Article
Li, JC; Feng, L; Sun, BH; Ikeda, T; Nohara, T
Published in: Biological & pharmaceutical bulletin
March 2005

A new xanthone derivative was isolated together with other 13 known constituents from a Chinese natural medicine, Swertia pseudochinensis HARA. Their structures were determined based on the spectral and chemical evidences. Furthermore, respective hexane, ethyl acetate, 1-BuOH, MeOH and water extracts of S. pseudochinensis, and purified compounds were respectively evaluated for their hepatoprotective activities against hepatocyte injury induced by CCl4. All the extracts and isolated compounds exhibited significant hepatoprotective activities at a dose showing no hepatoxicity.

Duke Scholars

Published In

Biological & pharmaceutical bulletin

ISSN

0918-6158

Publication Date

March 2005

Volume

28

Issue

3

Start / End Page

534 / 537

Location

japan

Related Subject Headings

  • Pharmacology & Pharmacy
  • 3404 Medicinal and biomolecular chemistry
  • 3214 Pharmacology and pharmaceutical sciences
  • 3101 Biochemistry and cell biology
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0607 Plant Biology
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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Li, J. C., Feng, L., Sun, B. H., Ikeda, T., & Nohara, T. (2005). Hepatoprotective activity of the constituents in Swertia pseudochinensis. Biological & Pharmaceutical Bulletin, 28(3), 534–537.
Li, J. C., L. Feng, B. H. Sun, T. Ikeda, and T. Nohara. “Hepatoprotective activity of the constituents in Swertia pseudochinensis.Biological & Pharmaceutical Bulletin 28, no. 3 (March 2005): 534–37.
Li JC, Feng L, Sun BH, Ikeda T, Nohara T. Hepatoprotective activity of the constituents in Swertia pseudochinensis. Biological & pharmaceutical bulletin. 2005 Mar;28(3):534–7.
Li, J. C., et al. “Hepatoprotective activity of the constituents in Swertia pseudochinensis.Biological & Pharmaceutical Bulletin, vol. 28, no. 3, Mar. 2005, pp. 534–37.
Li JC, Feng L, Sun BH, Ikeda T, Nohara T. Hepatoprotective activity of the constituents in Swertia pseudochinensis. Biological & pharmaceutical bulletin. 2005 Mar;28(3):534–537.

Published In

Biological & pharmaceutical bulletin

ISSN

0918-6158

Publication Date

March 2005

Volume

28

Issue

3

Start / End Page

534 / 537

Location

japan

Related Subject Headings

  • Pharmacology & Pharmacy
  • 3404 Medicinal and biomolecular chemistry
  • 3214 Pharmacology and pharmaceutical sciences
  • 3101 Biochemistry and cell biology
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0607 Plant Biology
  • 0304 Medicinal and Biomolecular Chemistry